FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3163297395> ?p ?o ?g. }

• W3163297395 endingPage "457" @default.
• W3163297395 startingPage "457" @default.
• W3163297395 abstract "Iguratimod (IGU) is a conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) routinely prescribed in Japan since 2012 to patients with rheumatoid arthritis (RA). Iguratimod acts directly on B cells by inhibiting the production of inflammatory cytokines (tumor necrosis factor-α, interleukin (IL)-1β, IL-6, IL-8, IL-17), thereby suppressing the production of immunoglobulin and inhibiting the activity of nuclear factor kappa-light chain enhancer of activated B cells. In Japan, it is one of the most used csDMARDs in daily practice, but it is not recommended as a treatment for RA due to the lack of large-scale evidence established overseas. However, recent reports on the novel pharmacological effects of IGU on lymphocytes and synovial fibroblasts, as well as its efficacy in daily practice, have increased its importance as a drug for the treatment of RA. In this review, we highlighted the basic and clinical studies in IGU and discuss its potential as a new therapeutic agent for the treatment of RA." @default.
• W3163297395 created "2021-05-24" @default.
• W3163297395 creator A5049739608 @default.
• W3163297395 date "2021-05-20" @default.
• W3163297395 modified "2023-10-02" @default.
• W3163297395 title "Iguratimod: Novel Molecular Insights and a New csDMARD for Rheumatoid Arthritis, from Japan to the World" @default.
• W3163297395 cites W1636221253 @default.
• W3163297395 cites W1977151536 @default.
• W3163297395 cites W1989273660 @default.
• W3163297395 cites W1999849541 @default.
• W3163297395 cites W2010675961 @default.
• W3163297395 cites W2012099358 @default.
• W3163297395 cites W2012419795 @default.
• W3163297395 cites W2024644107 @default.
• W3163297395 cites W2027778269 @default.
• W3163297395 cites W2029700855 @default.
• W3163297395 cites W2040375528 @default.
• W3163297395 cites W2046330020 @default.
• W3163297395 cites W2062697678 @default.
• W3163297395 cites W2068579674 @default.
• W3163297395 cites W2076953985 @default.
• W3163297395 cites W2089478514 @default.
• W3163297395 cites W2091039286 @default.
• W3163297395 cites W2106574491 @default.
• W3163297395 cites W2113482445 @default.
• W3163297395 cites W2121311666 @default.
• W3163297395 cites W2123632788 @default.
• W3163297395 cites W2133982451 @default.
• W3163297395 cites W2137384756 @default.
• W3163297395 cites W2144635371 @default.
• W3163297395 cites W2145188316 @default.
• W3163297395 cites W2149026148 @default.
• W3163297395 cites W2149469915 @default.
• W3163297395 cites W2155440550 @default.
• W3163297395 cites W2165459235 @default.
• W3163297395 cites W2181880346 @default.
• W3163297395 cites W2338295703 @default.
• W3163297395 cites W2540884398 @default.
• W3163297395 cites W2559774015 @default.
• W3163297395 cites W2636378421 @default.
• W3163297395 cites W2753002154 @default.
• W3163297395 cites W2767712942 @default.
• W3163297395 cites W2789695333 @default.
• W3163297395 cites W2796129073 @default.
• W3163297395 cites W2802373788 @default.
• W3163297395 cites W2806282383 @default.
• W3163297395 cites W2912943673 @default.
• W3163297395 cites W2945302694 @default.
• W3163297395 cites W2966041078 @default.
• W3163297395 cites W3007121258 @default.
• W3163297395 cites W3095553929 @default.
• W3163297395 cites W4243626754 @default.
• W3163297395 cites W4250908540 @default.
• W3163297395 cites W4251131605 @default.
• W3163297395 doi "https://doi.org/10.3390/life11050457" @default.
• W3163297395 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8160848" @default.
• W3163297395 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34065413" @default.
• W3163297395 hasPublicationYear "2021" @default.
• W3163297395 type Work @default.
• W3163297395 sameAs 3163297395 @default.
• W3163297395 citedByCount "6" @default.
• W3163297395 countsByYear W31632973952022 @default.
• W3163297395 countsByYear W31632973952023 @default.
• W3163297395 crossrefType "journal-article" @default.
• W3163297395 hasAuthorship W3163297395A5049739608 @default.
• W3163297395 hasBestOaLocation W31632973951 @default.
• W3163297395 hasConcept C126322002 @default.
• W3163297395 hasConcept C17991360 @default.
• W3163297395 hasConcept C1862650 @default.
• W3163297395 hasConcept C203014093 @default.
• W3163297395 hasConcept C2777575956 @default.
• W3163297395 hasConcept C2778690821 @default.
• W3163297395 hasConcept C2779974597 @default.
• W3163297395 hasConcept C2780035454 @default.
• W3163297395 hasConcept C502942594 @default.
• W3163297395 hasConcept C71924100 @default.
• W3163297395 hasConcept C74172505 @default.
• W3163297395 hasConcept C98274493 @default.
• W3163297395 hasConceptScore W3163297395C126322002 @default.
• W3163297395 hasConceptScore W3163297395C17991360 @default.
• W3163297395 hasConceptScore W3163297395C1862650 @default.
• W3163297395 hasConceptScore W3163297395C203014093 @default.
• W3163297395 hasConceptScore W3163297395C2777575956 @default.
• W3163297395 hasConceptScore W3163297395C2778690821 @default.
• W3163297395 hasConceptScore W3163297395C2779974597 @default.
• W3163297395 hasConceptScore W3163297395C2780035454 @default.
• W3163297395 hasConceptScore W3163297395C502942594 @default.
• W3163297395 hasConceptScore W3163297395C71924100 @default.
• W3163297395 hasConceptScore W3163297395C74172505 @default.
• W3163297395 hasConceptScore W3163297395C98274493 @default.
• W3163297395 hasIssue "5" @default.
• W3163297395 hasLocation W31632973951 @default.
• W3163297395 hasLocation W31632973952 @default.
• W3163297395 hasOpenAccess W3163297395 @default.
• W3163297395 hasPrimaryLocation W31632973951 @default.
• W3163297395 hasRelatedWork W1978139157 @default.
• W3163297395 hasRelatedWork W2006549602 @default.
• W3163297395 hasRelatedWork W2156283049 @default.

• next