Matches in SemOpenAlex for { <https://semopenalex.org/work/W3163411982> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3163411982 endingPage "153464" @default.
- W3163411982 startingPage "153464" @default.
- W3163411982 abstract "Lymph node status remains one of the most important determinants for prognosis in patients with invasive malignant melanoma. Immunohistochemical stains are routinely employed in the histopathologic evaluation of sentinel lymph nodes removed for staging in patients with melanoma. Histologic analysis may reveal the presence of incidental benign melanocytic nevus cell inclusions (BMNCI), which are critical to distinguish from metastatic melanoma (MM). Our study assesses the utility of NK1 C3 (CD63) immunohistochemical staining in distinguishing between MM and BMNCI in sentinel lymph nodes. We found no difference in staining of MM and BMNCI, precluding its usefulness in differentiating between benign and malignant melanocytes. Thus CD63 lacks specificity when facing challenging cases requiring distinction between benign and malignant melanocytic cells; however, in combination with other immunohistochemical antibodies, CD63 may be useful in supporting melanocytic differentiation. Distinguishing MM and BMNCI continues to be a diagnostic challenge at times. Further research is needed to identify potentially useful markers to provide better diagnostic utility when evaluating lymph node biopsies in patients with melanoma." @default.
- W3163411982 created "2021-05-24" @default.
- W3163411982 creator A5008440264 @default.
- W3163411982 creator A5038392356 @default.
- W3163411982 creator A5074465838 @default.
- W3163411982 date "2021-07-01" @default.
- W3163411982 modified "2023-09-27" @default.
- W3163411982 title "CD63 expression in metastatic melanoma and melanocytic nevi in lymph nodes" @default.
- W3163411982 cites W106986414 @default.
- W3163411982 cites W1965306336 @default.
- W3163411982 cites W1998500388 @default.
- W3163411982 cites W2075681407 @default.
- W3163411982 cites W2079521303 @default.
- W3163411982 cites W2080854153 @default.
- W3163411982 cites W2087757518 @default.
- W3163411982 cites W2088049678 @default.
- W3163411982 cites W2130377161 @default.
- W3163411982 cites W4233359376 @default.
- W3163411982 cites W4249035627 @default.
- W3163411982 doi "https://doi.org/10.1016/j.prp.2021.153464" @default.
- W3163411982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34051511" @default.
- W3163411982 hasPublicationYear "2021" @default.
- W3163411982 type Work @default.
- W3163411982 sameAs 3163411982 @default.
- W3163411982 citedByCount "0" @default.
- W3163411982 crossrefType "journal-article" @default.
- W3163411982 hasAuthorship W3163411982A5008440264 @default.
- W3163411982 hasAuthorship W3163411982A5038392356 @default.
- W3163411982 hasAuthorship W3163411982A5074465838 @default.
- W3163411982 hasConcept C104317684 @default.
- W3163411982 hasConcept C121608353 @default.
- W3163411982 hasConcept C126322002 @default.
- W3163411982 hasConcept C142724271 @default.
- W3163411982 hasConcept C145059251 @default.
- W3163411982 hasConcept C200583388 @default.
- W3163411982 hasConcept C204232928 @default.
- W3163411982 hasConcept C20518536 @default.
- W3163411982 hasConcept C2776385711 @default.
- W3163411982 hasConcept C2777411683 @default.
- W3163411982 hasConcept C2777658100 @default.
- W3163411982 hasConcept C2779323059 @default.
- W3163411982 hasConcept C2779720271 @default.
- W3163411982 hasConcept C2780212769 @default.
- W3163411982 hasConcept C2780849966 @default.
- W3163411982 hasConcept C502942594 @default.
- W3163411982 hasConcept C530470458 @default.
- W3163411982 hasConcept C549673821 @default.
- W3163411982 hasConcept C55493867 @default.
- W3163411982 hasConcept C71924100 @default.
- W3163411982 hasConcept C86803240 @default.
- W3163411982 hasConceptScore W3163411982C104317684 @default.
- W3163411982 hasConceptScore W3163411982C121608353 @default.
- W3163411982 hasConceptScore W3163411982C126322002 @default.
- W3163411982 hasConceptScore W3163411982C142724271 @default.
- W3163411982 hasConceptScore W3163411982C145059251 @default.
- W3163411982 hasConceptScore W3163411982C200583388 @default.
- W3163411982 hasConceptScore W3163411982C204232928 @default.
- W3163411982 hasConceptScore W3163411982C20518536 @default.
- W3163411982 hasConceptScore W3163411982C2776385711 @default.
- W3163411982 hasConceptScore W3163411982C2777411683 @default.
- W3163411982 hasConceptScore W3163411982C2777658100 @default.
- W3163411982 hasConceptScore W3163411982C2779323059 @default.
- W3163411982 hasConceptScore W3163411982C2779720271 @default.
- W3163411982 hasConceptScore W3163411982C2780212769 @default.
- W3163411982 hasConceptScore W3163411982C2780849966 @default.
- W3163411982 hasConceptScore W3163411982C502942594 @default.
- W3163411982 hasConceptScore W3163411982C530470458 @default.
- W3163411982 hasConceptScore W3163411982C549673821 @default.
- W3163411982 hasConceptScore W3163411982C55493867 @default.
- W3163411982 hasConceptScore W3163411982C71924100 @default.
- W3163411982 hasConceptScore W3163411982C86803240 @default.
- W3163411982 hasLocation W31634119821 @default.
- W3163411982 hasLocation W31634119822 @default.
- W3163411982 hasOpenAccess W3163411982 @default.
- W3163411982 hasPrimaryLocation W31634119821 @default.
- W3163411982 hasRelatedWork W1963841555 @default.
- W3163411982 hasRelatedWork W1988804311 @default.
- W3163411982 hasRelatedWork W2027197747 @default.
- W3163411982 hasRelatedWork W2031773369 @default.
- W3163411982 hasRelatedWork W2062130696 @default.
- W3163411982 hasRelatedWork W2072346290 @default.
- W3163411982 hasRelatedWork W236213871 @default.
- W3163411982 hasRelatedWork W2583408542 @default.
- W3163411982 hasRelatedWork W3015776079 @default.
- W3163411982 hasRelatedWork W3163411982 @default.
- W3163411982 hasVolume "223" @default.
- W3163411982 isParatext "false" @default.
- W3163411982 isRetracted "false" @default.
- W3163411982 magId "3163411982" @default.
- W3163411982 workType "article" @default.