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- W3163485281 abstract "A Mannich reaction of 2,2,2‐trifluoroethylamine hydrochloride, paraformaldehyde and acetophenone was described both in oil bath and microwave‐heating conditions to give main products varied from trifluoroethyl derived tertiary to secondary amine. In the microwave‐heating manner, the reaction was carried out in a commercial available microwave oven and took only 10 min to complete this transformation. After a simple post‐treatment including washing and recrystallization, the product of trifluoroethyl derived secondary amine was obtained in high yield (71.4%)." @default.
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- W3163485281 date "2021-05-10" @default.
- W3163485281 modified "2023-09-24" @default.
- W3163485281 title "Mannich Reaction as a Key Strategy for the Synthesis of Trifluoroethyl Derived Tertiary and Secondary Amine" @default.
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- W3163485281 doi "https://doi.org/10.1002/bkcs.12293" @default.
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