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• W3163760696 abstract "Objective: The aim of this study was to explore the expression and effects of tumor necrosis factor alpha (TNFα) in maternal endothelial cells in preeclampsia (PE).Methods: Expression levels in primary microvascular endothelial cells (MVEC) isolated from patients with severe preeclampsia (PE) and normal pregnancies were determined by RT-qPCR with or without treatment of TNFα and inhibitors for downstream signaling.Results: PE MVEC exhibited increased basal TNFα expression. TNFα treatment increased TNFα, VCAM, and endocan expression in MVEC.Conclusion: TNFα expression is increased in PE MVEC and the treatment of these cells with exogenous TNFα modifies their gene expression." @default.
• W3163760696 created "2021-05-24" @default.
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• W3163760696 date "2021-05-12" @default.
• W3163760696 modified "2023-10-16" @default.
• W3163760696 title "Tumor necrosis factor alpha expression is increased in maternal microvascular endothelial cells in preeclampsia" @default.
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• W3163760696 doi "https://doi.org/10.1080/10641955.2021.1921794" @default.
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