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- W3163927951 abstract "Abstract The onset of prominent viral diseases has created havoc globally due to incompetent countermeasures and delayed response to neutralize the viral manifestations. The new emerging viruses are posing serious threats to mankind and their enigmatic genomic constructions are of serious concern. The major hurdle in overcoming this problem is the insufficient availability of data and lack of their precise interpretation. To overwhelm this obstacle, virology is now amalgamated with bioinformatics, and this new entity is called viroinformatics. It comprises databases and webservers, from where large amounts of information about viruses (e.g., dengue virus, human immunodeficiency virus, hemorrhagic fever virus, human papillomavirus) can be retrieved. It also provides tools for distinct applications like comparative/diversity analysis, structural analysis, RNA folding, protein–protein interaction, multiple sequence alignment, 3D visualization, genotyping, etc. All information and their access cannot be availed from a particular source. Here, different sources of various information, tools, and other utilities used in virology will be presented, and this will open doors for new and effective therapeutic discoveries. It includes preparation of a major list of viroinformatics resources, categorization of these resources based on their specificity for a virus or task, and comparison of tools performing similar tasks concerning different criteria (priority, prevalence, fidelity; the vastness of genomic sequence pool; uniqueness of features; availability of web interface). These will enhance the feasibility of selecting suitable tools for performing a task." @default.
- W3163927951 created "2021-05-24" @default.
- W3163927951 creator A5049622510 @default.
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- W3163927951 date "2021-01-01" @default.
- W3163927951 modified "2023-09-25" @default.
- W3163927951 title "Viroinformatics: a modern approach to counter viral diseases through computational informatics" @default.
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- W3163927951 doi "https://doi.org/10.1016/b978-0-323-89824-9.00013-6" @default.
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