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- W3163968493 endingPage "2014" @default.
- W3163968493 startingPage "1987" @default.
- W3163968493 abstract "Bacteriophage immobilization is a key unit operation in emerging biotechnologies, enabling new possibilities for biodetection of pathogenic microbes at low concentration, production of materials with novel antimicrobial properties, and fundamental research on bacteriophages themselves. Wild type bacteriophages exhibit extreme binding specificity for a single species, and often for a particular subspecies, of bacteria. Since their specificity originates in epitope recognition by capsid proteins, which can be altered by chemical or genetic modification, their binding specificity may also be redirected toward arbitrary substrates and/or a variety of analytes in addition to bacteria. The immobilization of bacteriophages on planar and particulate substrates is thus an area of active and increasing scientific interest. This review assembles the knowledge gained so far in the immobilization of whole phage particles, summarizing the main chemistries, and presenting the current state-of-the-art both for an audience well-versed in bioconjugation methods as well as for those who are new to the field." @default.
- W3163968493 created "2021-06-07" @default.
- W3163968493 creator A5017042946 @default.
- W3163968493 creator A5026570351 @default.
- W3163968493 creator A5089116898 @default.
- W3163968493 date "2021-05-26" @default.
- W3163968493 modified "2023-10-18" @default.
- W3163968493 title "Strategies for Surface Immobilization of Whole Bacteriophages: A Review" @default.
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