Matches in SemOpenAlex for { <https://semopenalex.org/work/W3163993887> ?p ?o ?g. }
- W3163993887 abstract "Mobile genetic elements with circular genomes play a key role in the evolution of microbial communities. These circular genomes correspond to cyclic paths in metagenome graphs, and yet, assemblies derived from natural microbial communities produce graphs riddled with spurious cycles, complicating the accurate reconstruction of circular genomes. We present an algorithm that reconstructs true circular genomes based on the identification of so-called ‘dominant’ cycles. Our algorithm leverages paired reads to bridge gaps between assembly contigs and scrutinizes cycles through a nucleotide-level analysis, making the approach robust to mis-assembly artifacts. We validated the approach using simulated and reference data. Application of this approach to 32 publicly available DNA shotgun sequence data sets from diverse natural environments led to the reconstruction of hundreds of circular mobile genomes. Clustering revealed 20 clusters of cryptic, prevalent, and abundant plasmids that have clonal population structures with surprisingly recent common ancestors. This work enables the robust study of evolution and spread of mobile elements in natural settings." @default.
- W3163993887 created "2021-06-07" @default.
- W3163993887 creator A5008684312 @default.
- W3163993887 creator A5054337159 @default.
- W3163993887 creator A5058486161 @default.
- W3163993887 date "2021-05-26" @default.
- W3163993887 modified "2023-10-16" @default.
- W3163993887 title "Precise genotyping of circular mobile elements uncovers human associated plasmids with surprisingly recent common ancestors" @default.
- W3163993887 cites W1849979647 @default.
- W3163993887 cites W1911391407 @default.
- W3163993887 cites W1936330592 @default.
- W3163993887 cites W1966245151 @default.
- W3163993887 cites W1966912927 @default.
- W3163993887 cites W1996650392 @default.
- W3163993887 cites W2001561488 @default.
- W3163993887 cites W2027831845 @default.
- W3163993887 cites W2030709910 @default.
- W3163993887 cites W2058598212 @default.
- W3163993887 cites W2088861893 @default.
- W3163993887 cites W2104704801 @default.
- W3163993887 cites W2112148803 @default.
- W3163993887 cites W2119859604 @default.
- W3163993887 cites W2119902463 @default.
- W3163993887 cites W2130764575 @default.
- W3163993887 cites W2131415145 @default.
- W3163993887 cites W2137270994 @default.
- W3163993887 cites W2143325926 @default.
- W3163993887 cites W2305704688 @default.
- W3163993887 cites W2616477171 @default.
- W3163993887 cites W2790805631 @default.
- W3163993887 cites W2796402930 @default.
- W3163993887 cites W2796529794 @default.
- W3163993887 cites W2883838322 @default.
- W3163993887 cites W2891233979 @default.
- W3163993887 cites W2909601828 @default.
- W3163993887 cites W2921342657 @default.
- W3163993887 cites W2942757983 @default.
- W3163993887 cites W2950155065 @default.
- W3163993887 cites W2951325968 @default.
- W3163993887 cites W2951563276 @default.
- W3163993887 cites W2952926828 @default.
- W3163993887 cites W2970367351 @default.
- W3163993887 cites W2982130628 @default.
- W3163993887 cites W2994931131 @default.
- W3163993887 cites W2999493833 @default.
- W3163993887 cites W3005528502 @default.
- W3163993887 cites W3032971392 @default.
- W3163993887 cites W3035376931 @default.
- W3163993887 cites W3116417398 @default.
- W3163993887 cites W3118475094 @default.
- W3163993887 cites W3120084484 @default.
- W3163993887 doi "https://doi.org/10.1101/2021.05.25.445656" @default.
- W3163993887 hasPublicationYear "2021" @default.
- W3163993887 type Work @default.
- W3163993887 sameAs 3163993887 @default.
- W3163993887 citedByCount "0" @default.
- W3163993887 crossrefType "posted-content" @default.
- W3163993887 hasAuthorship W3163993887A5008684312 @default.
- W3163993887 hasAuthorship W3163993887A5054337159 @default.
- W3163993887 hasAuthorship W3163993887A5058486161 @default.
- W3163993887 hasBestOaLocation W31639938871 @default.
- W3163993887 hasConcept C104317684 @default.
- W3163993887 hasConcept C116834253 @default.
- W3163993887 hasConcept C119857082 @default.
- W3163993887 hasConcept C124101348 @default.
- W3163993887 hasConcept C132533263 @default.
- W3163993887 hasConcept C141231307 @default.
- W3163993887 hasConcept C144024400 @default.
- W3163993887 hasConcept C149923435 @default.
- W3163993887 hasConcept C15151743 @default.
- W3163993887 hasConcept C154945302 @default.
- W3163993887 hasConcept C2908647359 @default.
- W3163993887 hasConcept C41008148 @default.
- W3163993887 hasConcept C54355233 @default.
- W3163993887 hasConcept C59582021 @default.
- W3163993887 hasConcept C59822182 @default.
- W3163993887 hasConcept C70721500 @default.
- W3163993887 hasConcept C73555534 @default.
- W3163993887 hasConcept C78458016 @default.
- W3163993887 hasConcept C86803240 @default.
- W3163993887 hasConcept C97256817 @default.
- W3163993887 hasConceptScore W3163993887C104317684 @default.
- W3163993887 hasConceptScore W3163993887C116834253 @default.
- W3163993887 hasConceptScore W3163993887C119857082 @default.
- W3163993887 hasConceptScore W3163993887C124101348 @default.
- W3163993887 hasConceptScore W3163993887C132533263 @default.
- W3163993887 hasConceptScore W3163993887C141231307 @default.
- W3163993887 hasConceptScore W3163993887C144024400 @default.
- W3163993887 hasConceptScore W3163993887C149923435 @default.
- W3163993887 hasConceptScore W3163993887C15151743 @default.
- W3163993887 hasConceptScore W3163993887C154945302 @default.
- W3163993887 hasConceptScore W3163993887C2908647359 @default.
- W3163993887 hasConceptScore W3163993887C41008148 @default.
- W3163993887 hasConceptScore W3163993887C54355233 @default.
- W3163993887 hasConceptScore W3163993887C59582021 @default.
- W3163993887 hasConceptScore W3163993887C59822182 @default.
- W3163993887 hasConceptScore W3163993887C70721500 @default.
- W3163993887 hasConceptScore W3163993887C73555534 @default.
- W3163993887 hasConceptScore W3163993887C78458016 @default.
- W3163993887 hasConceptScore W3163993887C86803240 @default.