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• W3164049073 abstract "The computational finite element method (FEM) simulates biophysics problems to avoid tedious and costly clinical trials. The new technologies include numerous software tools for implementing finite element (FE) models. These models are used to enhance the clinicians’ abilities for planning the ablation procedure, leading to improved patient outcomes. For safe design, speedy progress, assessment, optimization of the simulated design, and prototyping for such a complex ablation system, Multiphysics simulation tools for biomedical problems have a significant role. These tools simulate the ablation system under study, including the applicator, energy source, tumor tissues, and healthy tissues, to find the best parameter settings and workflow to generate FE models. Then, an integration between the implemented simulation model and a commercial FE software to find the best design of the ablation applicator can be concluded. Accordingly, tumors in different tissues can be considered including the liver, skin, lung, and bone in the presence of the blood vessels or not based on the tumor location. Different tumor volumes at different locations in the affected organ can be studied using the simulation tools to reach the proper ablation system for effective pretreatment planning using the proposed ablation procedure. COMSOL Multiphysics® software is considered one of the most efficient simulation tools to model the test designs and the energy radiator that incorporates the radiometric recognition in the ablation device. It simulates the electromagnetic (EM) effects and thermal effect around the hardware part of the radiative applicator to regulate and find the most suitable radiometric performance under various conditions. In the simulation model, the bioheating effects and tissue ablation procedures including lasers, focused high-intensity sound, and low-/high-frequency EM radiation can be simulated for time-to-market reduction, safety/robustness of medical ablation devices, and critical examination with governmental approval. This chapter reports some simulation tools used in the ablation therapy process. It also highlights the role of FE models in the simulation. A detailed explanation of the interfaces of COMSOL Multiphysics for modeling an ablation problem is given." @default.
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• W3164049073 date "2021-01-01" @default.
• W3164049073 modified "2023-10-18" @default.
• W3164049073 title "COMSOL Multiphysics software for ablation system simulation" @default.
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• W3164049073 doi "https://doi.org/10.1016/b978-0-12-819544-4.00007-1" @default.
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