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- W3164230529 abstract "Ĺ˝ilnĂ trombembolickĂĄ nemoc se v pediatrickĂŠ populaci vyskytuje zĹĂdka, nicmĂŠnÄ v poslednĂch letech jejĂ incidence stoupĂĄ. Standardem v lĂŠÄbÄ tohoto onemocnÄnĂ u dÄtĂ jsou nynĂ nefrakcionovanĂ˝ heparin, nĂzkomolekulĂĄrnĂ hepariny a warfarin, pĹĂpadnÄ fondaparinux. NovÄ byla pro pediatrickou populaci schvĂĄlena i lĂŠÄba rivaroxabanem, kterĂ˝ ĹadĂme do skupiny pĹĂmĂ˝ch orĂĄlnĂch antikoagulanciĂ. Dle recentnĂ studie pouĹžitĂ rivaroxabanu v porovnĂĄnĂ se standardnĂ lĂŠÄbou tromboembolickĂŠ nemoci u dÄtskĂ˝ch pacientĹŻ nepĹedstavuje vyĹĄĹĄĂ riziko krvĂĄcenĂ, naopak byla pĹi jeho pouĹžitĂ popsĂĄna ÄastÄjĹĄĂ ĂşplnĂĄ regrese trombu a mĂŠnÄ ÄastĂŠ symptomatickĂŠ recidivy onemocnÄnĂ. VyuĹžitĂ pĹĂmĂ˝ch orĂĄlnĂch antikoagulanciĂ vzhledem k jejich perorĂĄlnĂmu podĂĄnĂ a absenci nutnosti pravidelnĂŠ laboratornĂ monitorace pĹedstavuje obzvlĂĄĹĄtÄ pro dÄtskĂŠ pacienty moĹžnost znaÄnÄ komfortnÄjĹĄĂ varianty lĂŠÄby." @default.
- W3164230529 created "2021-06-07" @default.
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- W3164230529 date "2021-05-26" @default.
- W3164230529 modified "2023-09-30" @default.
- W3164230529 title "Rivaroxaban for the treatment and prevention of reccurence of venous thromboembolism in children" @default.
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- W3164230529 doi "https://doi.org/10.36290/vnl.2021.038" @default.
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