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- W3164363855 abstract "Abstract Background: The PROMIS Preference score (PROPr) is a new generic preference-based health-related quality of life (HRQoL) score that can be used as a health state utility (HSU) score for quality-adjusted life years (QALYs) in cost-utility analyses (CUAs). It is the first HSU score based on item response theory (IRT) and has favorable psychometric properties. The PROPr combines the seven PROMIS domains: cognition, depression, fatigue, pain, physical function, sleep disturbance, and ability to participate in social roles and activities. It was developed based on preferences of the US general population. We aimed to validate the PROPr in a patient sample and to compare it to the EQ-5D. Methods: We collected PROPr and EQ-5D-5L data from 141 patients treated in the rheumatology and psychosomatic departments. We evaluated the convergent validity, reliability, known-groups construct validity, and ceiling and floor effects of the PROPr and compared those characteristics to those of the EQ-5D. Results: The mean PROPr (0.26, 95% CI: 0.23; 0.29) and the mean EQ-5D (0.44, 95% CI: 0.38; 0.51) differed significantly (d = 0.18, p < 0.001). The Pearson correlation coefficient between the two scores was r = 0.72. The PROPr and EQ-5D demonstrated high reliability and similar discrimination power across sex, age, and conditions. While the PROPr showed a floor effect, the EQ-5D showed a ceiling effect. Conclusion: PROPr and EQ-5D measure HSU differently. The PROPr shows a broader definition of perfect health, with a wider range of measurements at the top end. The previous results of excellent validity and precision were confirmed." @default.
- W3164363855 created "2021-06-07" @default.
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- W3164363855 date "2021-05-11" @default.
- W3164363855 modified "2023-09-30" @default.
- W3164363855 title "Validity, reliability, and ceiling and floor effects of the PROMIS Preference score (PROPr) in patients with rheumatological and psychosomatic conditions" @default.
- W3164363855 doi "https://doi.org/10.21203/rs.3.rs-478767/v1" @default.
- W3164363855 hasPublicationYear "2021" @default.
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