Matches in SemOpenAlex for { <https://semopenalex.org/work/W316442968> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W316442968 endingPage "43" @default.
- W316442968 startingPage "337" @default.
- W316442968 abstract "Vascular grafts lined with endothelial cells (EC) grown to confluence in culture before implantation may provide a thromboresistant flow surface. Growth of EC on and their adherence to currently available prosthetic materials under conditions of flow are two impediments remaining in the development of such a graft. To address these problems, 22 polytetrafluoroethylene grafts (PTFE) (5 cm by 4 mm inside diameter) were pretreated with collagen and fibronectin, seeded with 2 to 3 X 10(6) bovine aortic EC per graft, and placed in tissue culture (seeded grafts). Twenty-two grafts pretreated with collagen and fibronectin alone served as controls. After 2 weeks morphologic studies revealed that 20/22 seeded grafts were lined with a confluent endothelial layer. Indium 111-oxine was then used to label the EC-seeded grafts. After exposure to either low (25 ml/min) or high (200 ml/min) flow rates for 60 minutes in an in vitro circuit, examination of the luminal surface of the graft by light microscopy and scanning electron microscopy revealed minimal loss of EC. These findings were corroborated by radionuclide scans that showed an insignificant loss of the EC-associated indium label during exposure to flow (7% low flow, 11% high flow). Pretreatment of PTFE grafts with collagen and fibronectin thus promotes both attachment and adherence of EC even under flow conditions." @default.
- W316442968 created "2016-06-24" @default.
- W316442968 creator A5024057961 @default.
- W316442968 creator A5024268568 @default.
- W316442968 creator A5079223740 @default.
- W316442968 creator A5088279057 @default.
- W316442968 creator A5089073925 @default.
- W316442968 date "1986-03-01" @default.
- W316442968 modified "2023-10-16" @default.
- W316442968 title "The effect of flow on vascular endothelial cells grown in tissue culture on polytetrafluoroethylene grafts." @default.
- W316442968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3082028" @default.
- W316442968 hasPublicationYear "1986" @default.
- W316442968 type Work @default.
- W316442968 sameAs 316442968 @default.
- W316442968 citedByCount "13" @default.
- W316442968 countsByYear W3164429682014 @default.
- W316442968 crossrefType "journal-article" @default.
- W316442968 hasAuthorship W316442968A5024057961 @default.
- W316442968 hasAuthorship W316442968A5024268568 @default.
- W316442968 hasAuthorship W316442968A5079223740 @default.
- W316442968 hasAuthorship W316442968A5088279057 @default.
- W316442968 hasAuthorship W316442968A5089073925 @default.
- W316442968 hasConcept C123012128 @default.
- W316442968 hasConcept C136229726 @default.
- W316442968 hasConcept C141071460 @default.
- W316442968 hasConcept C142724271 @default.
- W316442968 hasConcept C159985019 @default.
- W316442968 hasConcept C185592680 @default.
- W316442968 hasConcept C189165786 @default.
- W316442968 hasConcept C192562407 @default.
- W316442968 hasConcept C202751555 @default.
- W316442968 hasConcept C203014093 @default.
- W316442968 hasConcept C2780557906 @default.
- W316442968 hasConcept C553184892 @default.
- W316442968 hasConcept C55493867 @default.
- W316442968 hasConcept C71924100 @default.
- W316442968 hasConcept C86492073 @default.
- W316442968 hasConcept C86803240 @default.
- W316442968 hasConcept C95444343 @default.
- W316442968 hasConceptScore W316442968C123012128 @default.
- W316442968 hasConceptScore W316442968C136229726 @default.
- W316442968 hasConceptScore W316442968C141071460 @default.
- W316442968 hasConceptScore W316442968C142724271 @default.
- W316442968 hasConceptScore W316442968C159985019 @default.
- W316442968 hasConceptScore W316442968C185592680 @default.
- W316442968 hasConceptScore W316442968C189165786 @default.
- W316442968 hasConceptScore W316442968C192562407 @default.
- W316442968 hasConceptScore W316442968C202751555 @default.
- W316442968 hasConceptScore W316442968C203014093 @default.
- W316442968 hasConceptScore W316442968C2780557906 @default.
- W316442968 hasConceptScore W316442968C553184892 @default.
- W316442968 hasConceptScore W316442968C55493867 @default.
- W316442968 hasConceptScore W316442968C71924100 @default.
- W316442968 hasConceptScore W316442968C86492073 @default.
- W316442968 hasConceptScore W316442968C86803240 @default.
- W316442968 hasConceptScore W316442968C95444343 @default.
- W316442968 hasIssue "3" @default.
- W316442968 hasLocation W3164429681 @default.
- W316442968 hasOpenAccess W316442968 @default.
- W316442968 hasPrimaryLocation W3164429681 @default.
- W316442968 hasRelatedWork W2016436247 @default.
- W316442968 hasRelatedWork W2018892227 @default.
- W316442968 hasRelatedWork W2111833591 @default.
- W316442968 hasRelatedWork W2132333860 @default.
- W316442968 hasRelatedWork W2143925514 @default.
- W316442968 hasRelatedWork W2152253795 @default.
- W316442968 hasRelatedWork W2400246441 @default.
- W316442968 hasRelatedWork W2409059732 @default.
- W316442968 hasRelatedWork W2414321854 @default.
- W316442968 hasRelatedWork W32476625 @default.
- W316442968 hasVolume "99" @default.
- W316442968 isParatext "false" @default.
- W316442968 isRetracted "false" @default.
- W316442968 magId "316442968" @default.
- W316442968 workType "article" @default.