Matches in SemOpenAlex for { <https://semopenalex.org/work/W3164507799> ?p ?o ?g. }
- W3164507799 endingPage "W335" @default.
- W3164507799 startingPage "W326" @default.
- W3164507799 abstract "Abstract Although several tools facilitating in silico drug design are available, their results are usually difficult to integrate with publicly available information or require further processing to be fully exploited. The rational design of multi-target ligands (polypharmacology) and the repositioning of known drugs towards unmet therapeutic needs (drug repurposing) have raised increasing attention in drug discovery, although they usually require careful planning of tailored drug design strategies. Computational tools and data-driven approaches can help to reveal novel valuable opportunities in these contexts, as they enable to efficiently mine publicly available chemical, biological, clinical, and disease-related data. Based on these premises, we developed LigAdvisor, a data-driven webserver which integrates information reported in DrugBank, Protein Data Bank, UniProt, Clinical Trials and Therapeutic Target Database into an intuitive platform, to facilitate drug discovery tasks as drug repurposing, polypharmacology, target fishing and profiling. As designed, LigAdvisor enables easy integration of similarity estimation results with clinical data, thereby allowing a more efficient exploitation of information in different drug discovery contexts. Users can also develop customizable drug design tasks on their own molecules, by means of ligand- and target-based search modes, and download their results. LigAdvisor is publicly available at https://ligadvisor.unimore.it/." @default.
- W3164507799 created "2021-06-07" @default.
- W3164507799 creator A5014912634 @default.
- W3164507799 creator A5036760548 @default.
- W3164507799 creator A5039800320 @default.
- W3164507799 creator A5047242993 @default.
- W3164507799 creator A5085808966 @default.
- W3164507799 date "2021-05-22" @default.
- W3164507799 modified "2023-10-15" @default.
- W3164507799 title "LigAdvisor: a versatile and user-friendly web-platform for drug design" @default.
- W3164507799 cites W1530167222 @default.
- W3164507799 cites W1835740130 @default.
- W3164507799 cites W1973462822 @default.
- W3164507799 cites W1976156018 @default.
- W3164507799 cites W1981214699 @default.
- W3164507799 cites W1985593098 @default.
- W3164507799 cites W2009015643 @default.
- W3164507799 cites W2013126815 @default.
- W3164507799 cites W2024993723 @default.
- W3164507799 cites W2025816743 @default.
- W3164507799 cites W2068320203 @default.
- W3164507799 cites W2080754816 @default.
- W3164507799 cites W2120869341 @default.
- W3164507799 cites W2130479394 @default.
- W3164507799 cites W2131272506 @default.
- W3164507799 cites W2163025055 @default.
- W3164507799 cites W2170419109 @default.
- W3164507799 cites W2246954848 @default.
- W3164507799 cites W2402506318 @default.
- W3164507799 cites W2512620329 @default.
- W3164507799 cites W2554073607 @default.
- W3164507799 cites W2558999090 @default.
- W3164507799 cites W2590907701 @default.
- W3164507799 cites W2598265731 @default.
- W3164507799 cites W2604527271 @default.
- W3164507799 cites W2606217927 @default.
- W3164507799 cites W2611425558 @default.
- W3164507799 cites W2612436700 @default.
- W3164507799 cites W2619948933 @default.
- W3164507799 cites W2767891136 @default.
- W3164507799 cites W2885426709 @default.
- W3164507799 cites W2894600215 @default.
- W3164507799 cites W2896002881 @default.
- W3164507799 cites W2902800472 @default.
- W3164507799 cites W2945199349 @default.
- W3164507799 cites W2945842918 @default.
- W3164507799 cites W2950860419 @default.
- W3164507799 cites W2971801381 @default.
- W3164507799 cites W2993071249 @default.
- W3164507799 cites W2996724914 @default.
- W3164507799 cites W3006508031 @default.
- W3164507799 cites W3010058077 @default.
- W3164507799 cites W3017154096 @default.
- W3164507799 cites W3046419426 @default.
- W3164507799 cites W3094084473 @default.
- W3164507799 cites W3097145107 @default.
- W3164507799 cites W3103314130 @default.
- W3164507799 cites W3112376646 @default.
- W3164507799 cites W4240082606 @default.
- W3164507799 doi "https://doi.org/10.1093/nar/gkab385" @default.
- W3164507799 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8262749" @default.
- W3164507799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34023895" @default.
- W3164507799 hasPublicationYear "2021" @default.
- W3164507799 type Work @default.
- W3164507799 sameAs 3164507799 @default.
- W3164507799 citedByCount "9" @default.
- W3164507799 countsByYear W31645077992021 @default.
- W3164507799 countsByYear W31645077992022 @default.
- W3164507799 countsByYear W31645077992023 @default.
- W3164507799 crossrefType "journal-article" @default.
- W3164507799 hasAuthorship W3164507799A5014912634 @default.
- W3164507799 hasAuthorship W3164507799A5036760548 @default.
- W3164507799 hasAuthorship W3164507799A5039800320 @default.
- W3164507799 hasAuthorship W3164507799A5047242993 @default.
- W3164507799 hasAuthorship W3164507799A5085808966 @default.
- W3164507799 hasBestOaLocation W31645077991 @default.
- W3164507799 hasConcept C103637391 @default.
- W3164507799 hasConcept C110875604 @default.
- W3164507799 hasConcept C111919701 @default.
- W3164507799 hasConcept C11392498 @default.
- W3164507799 hasConcept C136764020 @default.
- W3164507799 hasConcept C155261790 @default.
- W3164507799 hasConcept C187191949 @default.
- W3164507799 hasConcept C18903297 @default.
- W3164507799 hasConcept C2522767166 @default.
- W3164507799 hasConcept C2780035454 @default.
- W3164507799 hasConcept C41008148 @default.
- W3164507799 hasConcept C519536355 @default.
- W3164507799 hasConcept C60644358 @default.
- W3164507799 hasConcept C63222358 @default.
- W3164507799 hasConcept C72634772 @default.
- W3164507799 hasConcept C74187038 @default.
- W3164507799 hasConcept C77088390 @default.
- W3164507799 hasConcept C86803240 @default.
- W3164507799 hasConcept C98274493 @default.
- W3164507799 hasConceptScore W3164507799C103637391 @default.
- W3164507799 hasConceptScore W3164507799C110875604 @default.
- W3164507799 hasConceptScore W3164507799C111919701 @default.