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- W3164622010 abstract "The evolution of quantitative details (i.e. “parameter values”) of biological systems is highly under-researched. We use evolutionary algorithms to co-evolve parameters for a generic but biologically plausible topological differential equation model of nutrient uptake. In our model, evolving cells compete for a finite pool of nutrient resources. From our investigations it emerges that the choice of values is very important for the properties of the biological system. Our analysis also shows that clonal populations that are not subject to competition from other species best grow at a very slow rate. However, if there is co-evolutionary pressure, that is, if a population of clones has to compete with other cells, then the fast growth is essential, so as not to leave resources to the competitor. We find that this strategy, while favoured evolutionarily, is inef- ficient from an energetic point of view, that is less growth is achieved per unit of input nutrient. We conclude, that competition can lead to an evolutionary pressure towards inefficiency." @default.
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- W3164622010 date "2014-07-01" @default.
- W3164622010 modified "2023-10-18" @default.
- W3164622010 title "Evolving Biological Systems: Evolutionary Pressure to Inefficiency" @default.
- W3164622010 doi "https://doi.org/10.1162/978-0-262-32621-6-ch016" @default.
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