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- W3164703629 abstract "Tyreopatie mĂ´Ĺžu nepriaznivo ovplyvĹovaĹĽ koncepciu, udrĹžanie gravidity, zvyĹĄujĂş riziko komplikĂĄciĂ v gravidite, mĂ´Ĺžu maĹĽ negatĂvny vplyv na plod. Je preto potrebnĂŠ vÄas zachytiĹĽ ochorenia ĹĄtĂtnej ŞĞazy v populĂĄcii Ĺžien plĂĄnujĂşcich graviditu, resp. vo vÄasnom ĹĄtĂĄdiu tehotenstva. V Slovenskej republike je od roku 2009 platnĂŠ OdbornĂŠ usmernenie Ministerstva zdravotnĂctva Slovenskej republiky (OU MZ SR) pre diagnostiku a lieÄbu autoimunitnĂ˝ch ochorenĂ ĹĄtĂtnej ŞĞazy u Ĺžien v obdobĂ tehotenstva. V naĹĄich sĂşboroch sme u 666 pacientok hodnotili vÄasnosĹĽ realizĂĄcie skrĂningu v Äasovom rozmedzĂ rokov 2015-2017, laboratĂłrne parametre ĹĄtĂtnej ŞĞazy, poÄet gravidĂt a ich komplikĂĄcie, potrebu lieÄby levotyroxĂnom. Zistili sme, Ĺže realizĂĄcia skrĂningu bola posunutĂĄ do skorĹĄieho obdobia gravidity (11,4 gestaÄnĂ˝ týŞdeĹ v rokoch 2015/2016 vs 8,2 gestaÄnĂ˝ týŞdeĹ v rokoch 2016/2017), najviac odoslanĂ˝ch pacientok bolo v 1. trimestri gravidity (72 %), pozitivitu autoprotilĂĄtok proti tyreoperoxidĂĄze malo 81 % pacientok, klinickĂş hypotyreĂłzu 10 % pacientok, subklinickĂş hypotyreĂłzu 90 % pacientok, patolĂłgiu v gravidite 13 % pacientok. LieÄbu dostĂĄvalo 70 % pacientok. Je zjavnĂŠ, Ĺže s odstupom Äasu od zavedenia skrĂningu stĂşpa poÄet skrĂnovanĂ˝ch pacientok v 1. trimestri (83 % v rokoch 2016/2017). Z vĂ˝sledkov vidieĹĽ i vysokĂ˝ poÄet zachytenej pozitivity autoprotilĂĄtok. JednĂĄ sa teda o tie pacientky, ktorĂŠ by mali byĹĽ sledovanĂŠ a v prĂpade vzostupu hladiny tyreostimulaÄnĂŠho hormĂłnu (TSH) nad hornĂş hranicu normy pre danĂ˝ trimester aj lieÄenĂŠ. LieÄba minimalizuje riziko tehotenskĂ˝ch komplikĂĄciĂ." @default.
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- W3164703629 date "2017-09-01" @default.
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- W3164703629 title "Thyroid screening in pregnancy - guideline in practice" @default.
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- W3164703629 doi "https://doi.org/10.36290/vnl.2017.112" @default.
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