FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3164756530> ?p ?o ?g. }

• W3164756530 endingPage "1127" @default.
• W3164756530 startingPage "1120" @default.
• W3164756530 abstract "To compare both the faecal bile acids (BAs) and the levels of two bile acid receptors, Takeda G protein-coupled receptor 5 (TGR5) and vitamin D receptor (VDR), in the colonic mucosa between patients with irritable bowel syndrome with predominant diarrhea (IBS-D) and healthy controls, and explore the correlations among clinical characteristics, bile acid receptors expression, and BAs.The severity of abdominal pain and diarrhoea was assessed in IBS-D patients using validated questionnaires, faecal BAs were measured by ultraperformance liquid chromatography coupled to tandem mass spectrometry, and rectosigmoid biopsies were taken for the analyses of TGR5 and VDR expression using immunohistochemistry.The level of TGR5 immunoreactivity in rectosigmoid mucosal biopsies was significantly higher in IBS-D patients than in controls, while the VDR immunoreactivity displayed no significant difference between patients and controls. The patients with more severe or more frequent abdominal pain had significantly higher TGR5 level. Faecal primary BAs were significantly increased in IBS-D patients and were positively correlated with the severity of diarrhoea. The level of TGR5 was positively associated with primary BAs and negatively associated with secondary BAs among all participants providing both mucosal and stool samples.Colonic mucosal TGR5 protein expression and faecal bile acids were correlated with the symptom severity of IBS-D patients." @default.
• W3164756530 created "2021-06-07" @default.
• W3164756530 creator A5003799076 @default.
• W3164756530 creator A5015145411 @default.
• W3164756530 creator A5030849116 @default.
• W3164756530 creator A5035859462 @default.
• W3164756530 creator A5038741949 @default.
• W3164756530 creator A5072453373 @default.
• W3164756530 creator A5080176760 @default.
• W3164756530 creator A5081826628 @default.
• W3164756530 date "2021-09-01" @default.
• W3164756530 modified "2023-09-26" @default.
• W3164756530 title "Faecal bile acids and colonic bile acid membrane receptor correlate with symptom severity of diarrhoea-predominant irritable bowel syndrome: A pilot study" @default.
• W3164756530 cites W1482883615 @default.
• W3164756530 cites W1947293956 @default.
• W3164756530 cites W1964081409 @default.
• W3164756530 cites W1971384756 @default.
• W3164756530 cites W1976068711 @default.
• W3164756530 cites W1979028527 @default.
• W3164756530 cites W1980616954 @default.
• W3164756530 cites W2003525898 @default.
• W3164756530 cites W2003559422 @default.
• W3164756530 cites W2021206718 @default.
• W3164756530 cites W2021663771 @default.
• W3164756530 cites W2031686588 @default.
• W3164756530 cites W2040743397 @default.
• W3164756530 cites W2044552768 @default.
• W3164756530 cites W2044635500 @default.
• W3164756530 cites W2049169935 @default.
• W3164756530 cites W2052578516 @default.
• W3164756530 cites W2057463828 @default.
• W3164756530 cites W2066299684 @default.
• W3164756530 cites W2068663235 @default.
• W3164756530 cites W2076995479 @default.
• W3164756530 cites W2090171320 @default.
• W3164756530 cites W2092469452 @default.
• W3164756530 cites W2095053527 @default.
• W3164756530 cites W2096418655 @default.
• W3164756530 cites W2099165053 @default.
• W3164756530 cites W2100311096 @default.
• W3164756530 cites W2124975651 @default.
• W3164756530 cites W2137645401 @default.
• W3164756530 cites W2142544310 @default.
• W3164756530 cites W2146589073 @default.
• W3164756530 cites W2150113459 @default.
• W3164756530 cites W2150807020 @default.
• W3164756530 cites W2157906581 @default.
• W3164756530 cites W2314167679 @default.
• W3164756530 cites W2326552171 @default.
• W3164756530 cites W2344997643 @default.
• W3164756530 cites W2428595929 @default.
• W3164756530 cites W2438251162 @default.
• W3164756530 cites W2549879827 @default.
• W3164756530 cites W2549880305 @default.
• W3164756530 cites W2784137104 @default.
• W3164756530 cites W2807580748 @default.
• W3164756530 cites W2808056681 @default.
• W3164756530 cites W2894156089 @default.
• W3164756530 cites W2894410079 @default.
• W3164756530 cites W2897639202 @default.
• W3164756530 cites W2897647069 @default.
• W3164756530 cites W2908667100 @default.
• W3164756530 cites W2908667400 @default.
• W3164756530 cites W2914927457 @default.
• W3164756530 cites W2945994944 @default.
• W3164756530 cites W2951485248 @default.
• W3164756530 cites W2974548772 @default.
• W3164756530 cites W2993103758 @default.
• W3164756530 cites W3011952615 @default.
• W3164756530 cites W3023701859 @default.
• W3164756530 cites W3080457950 @default.
• W3164756530 cites W3106718012 @default.
• W3164756530 doi "https://doi.org/10.1016/j.dld.2021.04.022" @default.
• W3164756530 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34053874" @default.
• W3164756530 hasPublicationYear "2021" @default.
• W3164756530 type Work @default.
• W3164756530 sameAs 3164756530 @default.
• W3164756530 citedByCount "9" @default.
• W3164756530 countsByYear W31647565302021 @default.
• W3164756530 countsByYear W31647565302022 @default.
• W3164756530 countsByYear W31647565302023 @default.
• W3164756530 crossrefType "journal-article" @default.
• W3164756530 hasAuthorship W3164756530A5003799076 @default.
• W3164756530 hasAuthorship W3164756530A5015145411 @default.
• W3164756530 hasAuthorship W3164756530A5030849116 @default.
• W3164756530 hasAuthorship W3164756530A5035859462 @default.
• W3164756530 hasAuthorship W3164756530A5038741949 @default.
• W3164756530 hasAuthorship W3164756530A5072453373 @default.
• W3164756530 hasAuthorship W3164756530A5080176760 @default.
• W3164756530 hasAuthorship W3164756530A5081826628 @default.
• W3164756530 hasConcept C126322002 @default.
• W3164756530 hasConcept C151730666 @default.
• W3164756530 hasConcept C170493617 @default.
• W3164756530 hasConcept C179639408 @default.
• W3164756530 hasConcept C204232928 @default.
• W3164756530 hasConcept C2778271842 @default.
• W3164756530 hasConcept C2779399885 @default.
• W3164756530 hasConcept C2779802037 @default.

• next