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- W3164859345 abstract "Abstract Hepatocellular carcinoma (HCC) is a common liver malignancy. Early vascular invasion (VI) has been associated with poor prognosis in HCC patients. MicroRNAs (miRNAs) play a significant role in the emergence and development of many tumor types. In this study, we identified miR-9-5p that could predict VI and prognosis in HCC patients based on TCGA database. Further, we explored the possible mechanism of miR-9-5p by target gene prediction, functional enrichment analysis, and protein‑protein interaction analysis. Univariate and multivariate analysis revealed that miR-9-5p was an independent risk factor for HCC. Finally, the nomogram based on miR-9-5p showed a good predictive value of HCC survival. In summary, miR-9-5p is associated with VI in HCC, and higher expression of miR-9-5p indicates poor prognosis in HCC." @default.
- W3164859345 created "2021-06-07" @default.
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- W3164859345 date "2021-05-22" @default.
- W3164859345 modified "2023-10-16" @default.
- W3164859345 title "miR-9-5p Expression is Associated With Vascular Invasion and Prognosis in Hepatocellular Carcinoma" @default.
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- W3164859345 doi "https://doi.org/10.21203/rs.3.rs-527753/v1" @default.
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