Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165016349> ?p ?o ?g. }
- W3165016349 abstract "The microbiome plays an important role in maintaining human health. Despite multiple factors being attributed to the shaping of the human microbiome, extrinsic factors such diet and use of medications including antibiotics appear to dominate. Mucosal surfaces, particularly in the gut, are highly adapted to be able to tolerate a large population of microorganisms whilst still being able to produce a rapid and effective immune response against infection. The intestinal microbiome is not functionally independent from the host mucosa and can, through presentation of microbe-associated molecular patterns (MAMPs) and generation of microbe-derived metabolites, fundamentally influence mucosal barrier integrity and modulate host immunity. In a healthy gut there is an abundance of beneficial bacteria that help to preserve intestinal homoeostasis, promote protective immune responses, and limit excessive inflammation. The importance of the microbiome is further highlighted during dysbiosis where a loss of this finely balanced microbial population can lead to mucosal barrier dysfunction, aberrant immune responses, and chronic inflammation that increases the risk of disease development. Improvements in our understanding of the microbiome are providing opportunities to harness members of a healthy microbiota to help reverse dysbiosis, reduce inflammation, and ultimately prevent disease progression." @default.
- W3165016349 created "2021-06-07" @default.
- W3165016349 creator A5030435316 @default.
- W3165016349 creator A5032730075 @default.
- W3165016349 creator A5051642332 @default.
- W3165016349 creator A5086734835 @default.
- W3165016349 creator A5089390180 @default.
- W3165016349 date "2021-06-01" @default.
- W3165016349 modified "2023-10-17" @default.
- W3165016349 title "The role of the microbiome in gastrointestinal inflammation" @default.
- W3165016349 cites W143136217 @default.
- W3165016349 cites W1431584087 @default.
- W3165016349 cites W1505136191 @default.
- W3165016349 cites W1557339302 @default.
- W3165016349 cites W1564013339 @default.
- W3165016349 cites W1587501597 @default.
- W3165016349 cites W1608086249 @default.
- W3165016349 cites W1778862690 @default.
- W3165016349 cites W1785027726 @default.
- W3165016349 cites W1820461377 @default.
- W3165016349 cites W1832474145 @default.
- W3165016349 cites W1866740209 @default.
- W3165016349 cites W1868276939 @default.
- W3165016349 cites W1921871707 @default.
- W3165016349 cites W1922079366 @default.
- W3165016349 cites W1939083767 @default.
- W3165016349 cites W1953168141 @default.
- W3165016349 cites W1963907728 @default.
- W3165016349 cites W1965027165 @default.
- W3165016349 cites W1966423019 @default.
- W3165016349 cites W1968105193 @default.
- W3165016349 cites W1969699774 @default.
- W3165016349 cites W1972505691 @default.
- W3165016349 cites W1975296949 @default.
- W3165016349 cites W1977536320 @default.
- W3165016349 cites W197804012 @default.
- W3165016349 cites W1981266729 @default.
- W3165016349 cites W1982685134 @default.
- W3165016349 cites W1983422325 @default.
- W3165016349 cites W1989478912 @default.
- W3165016349 cites W1993399595 @default.
- W3165016349 cites W1994668628 @default.
- W3165016349 cites W1995924556 @default.
- W3165016349 cites W1996933969 @default.
- W3165016349 cites W2000311971 @default.
- W3165016349 cites W2000785566 @default.
- W3165016349 cites W2003342633 @default.
- W3165016349 cites W2004774344 @default.
- W3165016349 cites W2006055431 @default.
- W3165016349 cites W2008733625 @default.
- W3165016349 cites W2016539998 @default.
- W3165016349 cites W2018861313 @default.
- W3165016349 cites W2019427304 @default.
- W3165016349 cites W2020460418 @default.
- W3165016349 cites W2021208119 @default.
- W3165016349 cites W2022760114 @default.
- W3165016349 cites W2023007981 @default.
- W3165016349 cites W2023506796 @default.
- W3165016349 cites W2026658658 @default.
- W3165016349 cites W2030091490 @default.
- W3165016349 cites W2032605132 @default.
- W3165016349 cites W2034157397 @default.
- W3165016349 cites W2035421462 @default.
- W3165016349 cites W2036495967 @default.
- W3165016349 cites W2037347206 @default.
- W3165016349 cites W2037701117 @default.
- W3165016349 cites W2038429516 @default.
- W3165016349 cites W2040501063 @default.
- W3165016349 cites W2042074642 @default.
- W3165016349 cites W2042433863 @default.
- W3165016349 cites W2043442946 @default.
- W3165016349 cites W2044216294 @default.
- W3165016349 cites W2045897279 @default.
- W3165016349 cites W2047972199 @default.
- W3165016349 cites W2049448291 @default.
- W3165016349 cites W2052584095 @default.
- W3165016349 cites W2055291719 @default.
- W3165016349 cites W2063890406 @default.
- W3165016349 cites W2065252029 @default.
- W3165016349 cites W2070879762 @default.
- W3165016349 cites W2071841602 @default.
- W3165016349 cites W2072417345 @default.
- W3165016349 cites W2073714219 @default.
- W3165016349 cites W2077088073 @default.
- W3165016349 cites W2077553363 @default.
- W3165016349 cites W2078455937 @default.
- W3165016349 cites W2078908888 @default.
- W3165016349 cites W2079183971 @default.
- W3165016349 cites W2080086899 @default.
- W3165016349 cites W2080906449 @default.
- W3165016349 cites W2083089709 @default.
- W3165016349 cites W2083119809 @default.
- W3165016349 cites W2085284704 @default.
- W3165016349 cites W2086216523 @default.
- W3165016349 cites W2087278385 @default.
- W3165016349 cites W2087292184 @default.
- W3165016349 cites W2092648379 @default.
- W3165016349 cites W2095858949 @default.
- W3165016349 cites W2097855460 @default.
- W3165016349 cites W2107369528 @default.