Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165062922> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W3165062922 abstract "Background: Micronutrients has roles in strengthening and maintaining immune function, but its supplementation and/or deficiency effects on respiratory tract infections are inconclusive. This review aims to systematically assess the associations between micronutrient supplementation or deficiency, with novel coronavirus incidence and disease severity. Methods: Systematic literature searches conducted in 5 electronic databases identified 751 unique studies, of which 33 studies (5 supplementation studies, 1 supplementation and deficiency study, and 27 deficiency studies) were eventually included in this review. Proportions of incidence and severity outcomes in each group, and adjusted summary statistics with their relevant 95% confidence intervaIs (CI) were extracted. Data from 19 studies were pooled in meta-analysis using the generic inverse variance method. Findings: A total of 360,346 patients across 16 countries, with a mean age between 32 and 87.7 years, were involved across 33 studies. All studies were on COVID-19 infections. In individuals without micronutrient deficiency, there was a significant reduction on odds of COVID-19 incidence (pooled OR: 0.37, 95% CI: 0.18, 0.78), and ICU admissions or severe/critical disease onset (pooled OR: 0.26, 95% CI: 0.08, 0.89). Insignificant protective effects were observed on other outcome measures – mortality, ICU admission, progression to respiratory-related complications, severe/critical disease onset or requiring respiratory support and hospitalization rate. Conclusion: The absence of micronutrient deficiency significantly reduced COVID-19 incidence and clinical deterioration in hospitalized patients. Usage of micronutrients as prophylaxis and complementary supplement in therapeutic management of COVID-19 patients may be a promising and cost-effective approach warranting in-depth investigation." @default.
- W3165062922 created "2021-06-07" @default.
- W3165062922 creator A5014917559 @default.
- W3165062922 creator A5044590307 @default.
- W3165062922 creator A5077856266 @default.
- W3165062922 date "2021-04-01" @default.
- W3165062922 modified "2023-09-27" @default.
- W3165062922 title "Micronutrients Deficiency, Supplementation and Novel Coronavirus Infections–A Systematic Review and Meta-Analysis" @default.
- W3165062922 doi "https://doi.org/10.20944/preprints202104.0008.v1" @default.
- W3165062922 hasPublicationYear "2021" @default.
- W3165062922 type Work @default.
- W3165062922 sameAs 3165062922 @default.
- W3165062922 citedByCount "0" @default.
- W3165062922 crossrefType "posted-content" @default.
- W3165062922 hasAuthorship W3165062922A5014917559 @default.
- W3165062922 hasAuthorship W3165062922A5044590307 @default.
- W3165062922 hasAuthorship W3165062922A5077856266 @default.
- W3165062922 hasBestOaLocation W31650629221 @default.
- W3165062922 hasConcept C120665830 @default.
- W3165062922 hasConcept C121332964 @default.
- W3165062922 hasConcept C126322002 @default.
- W3165062922 hasConcept C142724271 @default.
- W3165062922 hasConcept C14522933 @default.
- W3165062922 hasConcept C156957248 @default.
- W3165062922 hasConcept C187212893 @default.
- W3165062922 hasConcept C2776012195 @default.
- W3165062922 hasConcept C2778596745 @default.
- W3165062922 hasConcept C2779134260 @default.
- W3165062922 hasConcept C534529494 @default.
- W3165062922 hasConcept C61511704 @default.
- W3165062922 hasConcept C71924100 @default.
- W3165062922 hasConcept C95190672 @default.
- W3165062922 hasConceptScore W3165062922C120665830 @default.
- W3165062922 hasConceptScore W3165062922C121332964 @default.
- W3165062922 hasConceptScore W3165062922C126322002 @default.
- W3165062922 hasConceptScore W3165062922C142724271 @default.
- W3165062922 hasConceptScore W3165062922C14522933 @default.
- W3165062922 hasConceptScore W3165062922C156957248 @default.
- W3165062922 hasConceptScore W3165062922C187212893 @default.
- W3165062922 hasConceptScore W3165062922C2776012195 @default.
- W3165062922 hasConceptScore W3165062922C2778596745 @default.
- W3165062922 hasConceptScore W3165062922C2779134260 @default.
- W3165062922 hasConceptScore W3165062922C534529494 @default.
- W3165062922 hasConceptScore W3165062922C61511704 @default.
- W3165062922 hasConceptScore W3165062922C71924100 @default.
- W3165062922 hasConceptScore W3165062922C95190672 @default.
- W3165062922 hasLocation W31650629221 @default.
- W3165062922 hasLocation W31650629222 @default.
- W3165062922 hasOpenAccess W3165062922 @default.
- W3165062922 hasPrimaryLocation W31650629221 @default.
- W3165062922 hasRelatedWork W2093591044 @default.
- W3165062922 hasRelatedWork W2209214969 @default.
- W3165062922 hasRelatedWork W2996164788 @default.
- W3165062922 hasRelatedWork W3093580200 @default.
- W3165062922 hasRelatedWork W3109900388 @default.
- W3165062922 hasRelatedWork W3125790204 @default.
- W3165062922 hasRelatedWork W4210515385 @default.
- W3165062922 hasRelatedWork W4312231765 @default.
- W3165062922 hasRelatedWork W75697074 @default.
- W3165062922 hasRelatedWork W93159522 @default.
- W3165062922 isParatext "false" @default.
- W3165062922 isRetracted "false" @default.
- W3165062922 magId "3165062922" @default.
- W3165062922 workType "article" @default.