Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165109247> ?p ?o ?g. }
- W3165109247 abstract "Abstract Innate and adaptive immune systems have a crucial role in initiating and progressing some pregnancy disorders such as preeclampsia (PE), which is one of the pregnancy‐specific disorders that could result in neonatal and maternal morbidity and mortality. The dysregulation of the spiral artery and inadequate trophoblast invasion lead to PE symptoms through producing various inflammatory cytokines and anti‐angiogenic factors from the placenta. T lymphocytes play a special role in the epithelium and stroma of the human endometrium. CD4+ T helper (Th) cells, Th1/Th2, and Th17/T regulatory (Treg) balance mainly contribute to the establishment of a pregnancy‐favorable environment. This review examined the dysregulation of some cytokines produced from T cells, the dysregulation of the transcription factors of Th cells, the expression of chemokine receptors on T cells, as well as the effects of some factors including vitamin D on the activity of T cells, and finally, the dysregulation of various miRNAs related to T cells, which could cause PE." @default.
- W3165109247 created "2021-06-07" @default.
- W3165109247 creator A5016541481 @default.
- W3165109247 creator A5031778899 @default.
- W3165109247 creator A5045135548 @default.
- W3165109247 creator A5050896650 @default.
- W3165109247 creator A5053968558 @default.
- W3165109247 creator A5056197706 @default.
- W3165109247 creator A5072759236 @default.
- W3165109247 date "2021-06-16" @default.
- W3165109247 modified "2023-10-16" @default.
- W3165109247 title "T lymphocytes and preeclampsia: The potential role of T‐cell subsets and related MicroRNAs in the pathogenesis of preeclampsia" @default.
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