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• W3165410273 abstract "Lung pleomorphic carcinoma (LPC) is generally resistant to chemotherapy or radiotherapy. However, a combination of immune checkpoint inhibitors and radiotherapy has a remarkable efficacy against LPC.Here, we report the case of a 50-year old man diagnosed with progressive LPC. The tumor invaded the carina and predominantly obstructed the right main bronchus; therefore, a combination of palliative chemoradiotherapy and atezolizumab was initiated. However the trachea was gradually obstructed.Argon plasma coagulation (APC) was performed to prevent tumor invasion. After three APC sessions, the tumor showed a necrotic change and was easily excised using biopsy forceps.A combination of chemoradiotherapy, atezolizumab, and APC showed a good efficacy, and the patient had a good response to atezolizumab maintenance therapy. Multidisciplinary treatments, such as a combination of immune checkpoint inhibitors and APC, could have synergistic efficacy in lung cancer." @default.
• W3165410273 created "2021-06-07" @default.
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• W3165410273 date "2021-05-28" @default.
• W3165410273 modified "2023-10-14" @default.
• W3165410273 title "Argon plasma coagulation with atezolizumab and chemoradiation in lung pleomorphic cancer showed a remarkable response" @default.
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• W3165410273 doi "https://doi.org/10.1097/md.0000000000026149" @default.
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