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- W3165438909 abstract "A 3-year-old girl presented with leg deformities diagnosed as enchondromatosis (Ollier disease), which is a rare, sporadic, skeletal disorder characterized by hamartomatous growth of cartilage cells within metaphyses of long bones. In 2008, fluid-attenuated inversion recovery signal hyperintensity in her left frontal lobe (Figure, A) and skull-base enchondroma (Figure, B) were discovered. Her enchondromatosis required amputation of digits that were heavy and unusable (Figure, C and D). In 2017, surveillance imaging revealed enlargement of the frontal tumor, leading to craniotomy for a WHO grade 2 astrocytoma. Ollier disease is associated with IDH mutations1 and patients must be monitored for sarcomatous transformation of enchondromas and extraosseous malignancies including gliomas.2" @default.
- W3165438909 created "2021-06-07" @default.
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- W3165438909 date "2021-10-26" @default.
- W3165438909 modified "2023-10-14" @default.
- W3165438909 title "Teaching NeuroImage: Histopathologically Confirmed Intracranial Enchondroma/Low-Grade Chondrosarcoma and IDH1-Mutated Diffuse Glioma in Ollier Disease" @default.
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- W3165438909 doi "https://doi.org/10.1212/wnl.0000000000012269" @default.
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