FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165547188> ?p ?o ?g. }

• W3165547188 endingPage "4498" @default.
• W3165547188 startingPage "4493" @default.
• W3165547188 abstract "Nucleophilic aromatic fluorination (SNAr) is among the most common methods for the formation of C(sp2)–F bonds. Despite many recent advances, a long-standing limitation of these transformations is the requirement for rigorously dry, aprotic conditions to maintain the nucleophilicity of fluoride and suppress the generation of side products. This report addresses this challenge by leveraging tetramethylammonium fluoride alcohol adducts (Me4NF·ROH) as fluoride sources for SNAr fluorination. Through systematic tuning of the alcohol substituent (R), tetramethylammonium fluoride tert-amyl alcohol (Me4NF·t-AmylOH) was identified as an inexpensive, practical, and bench-stable reagent for SNAr fluorination under mild and convenient conditions (80 °C in DMSO, without the requirement for drying of reagents or solvent). A substrate scope of more than 50 (hetero) aryl halides and nitroarene electrophiles is demonstrated." @default.
• W3165547188 created "2021-06-07" @default.
• W3165547188 creator A5003455653 @default.
• W3165547188 creator A5028785945 @default.
• W3165547188 creator A5032425304 @default.
• W3165547188 creator A5055990329 @default.
• W3165547188 creator A5085509535 @default.
• W3165547188 creator A5090764373 @default.
• W3165547188 date "2021-05-24" @default.
• W3165547188 modified "2023-09-27" @default.
• W3165547188 title "Tetramethylammonium Fluoride Alcohol Adducts for S_NAr Fluorination" @default.
• W3165547188 cites W1183155069 @default.
• W3165547188 cites W1924927508 @default.
• W3165547188 cites W1964305404 @default.
• W3165547188 cites W1973311993 @default.
• W3165547188 cites W1976866491 @default.
• W3165547188 cites W1977351611 @default.
• W3165547188 cites W1991937477 @default.
• W3165547188 cites W1993195042 @default.
• W3165547188 cites W1995689598 @default.
• W3165547188 cites W2012404887 @default.
• W3165547188 cites W2035437199 @default.
• W3165547188 cites W2046880515 @default.
• W3165547188 cites W2049419532 @default.
• W3165547188 cites W2057509100 @default.
• W3165547188 cites W2059512398 @default.
• W3165547188 cites W2065834277 @default.
• W3165547188 cites W2084301636 @default.
• W3165547188 cites W2094317287 @default.
• W3165547188 cites W2108558461 @default.
• W3165547188 cites W2116087305 @default.
• W3165547188 cites W2208465844 @default.
• W3165547188 cites W2319070004 @default.
• W3165547188 cites W2333129245 @default.
• W3165547188 cites W2410103223 @default.
• W3165547188 cites W2514191390 @default.
• W3165547188 cites W2549042810 @default.
• W3165547188 cites W2582455051 @default.
• W3165547188 cites W2611545088 @default.
• W3165547188 cites W2749221743 @default.
• W3165547188 cites W2766518285 @default.
• W3165547188 cites W2889367399 @default.
• W3165547188 cites W2951814994 @default.
• W3165547188 cites W2999233022 @default.
• W3165547188 cites W3046600537 @default.
• W3165547188 cites W3088065718 @default.
• W3165547188 cites W3131125915 @default.
• W3165547188 cites W4251094230 @default.
• W3165547188 cites W4362204496 @default.
• W3165547188 doi "https://doi.org/10.1021/acs.orglett.1c01490" @default.
• W3165547188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34029110" @default.
• W3165547188 hasPublicationYear "2021" @default.
• W3165547188 type Work @default.
• W3165547188 sameAs 3165547188 @default.
• W3165547188 citedByCount "12" @default.
• W3165547188 countsByYear W31655471882021 @default.
• W3165547188 countsByYear W31655471882022 @default.
• W3165547188 countsByYear W31655471882023 @default.
• W3165547188 crossrefType "journal-article" @default.
• W3165547188 hasAuthorship W3165547188A5003455653 @default.
• W3165547188 hasAuthorship W3165547188A5028785945 @default.
• W3165547188 hasAuthorship W3165547188A5032425304 @default.
• W3165547188 hasAuthorship W3165547188A5055990329 @default.
• W3165547188 hasAuthorship W3165547188A5085509535 @default.
• W3165547188 hasAuthorship W3165547188A5090764373 @default.
• W3165547188 hasBestOaLocation W31655471882 @default.
• W3165547188 hasConcept C108204754 @default.
• W3165547188 hasConcept C135731615 @default.
• W3165547188 hasConcept C145148216 @default.
• W3165547188 hasConcept C155647269 @default.
• W3165547188 hasConcept C161790260 @default.
• W3165547188 hasConcept C178790620 @default.
• W3165547188 hasConcept C178907741 @default.
• W3165547188 hasConcept C179104552 @default.
• W3165547188 hasConcept C185592680 @default.
• W3165547188 hasConcept C2778689049 @default.
• W3165547188 hasConcept C2780263894 @default.
• W3165547188 hasConcept C2780471494 @default.
• W3165547188 hasConcept C2780828025 @default.
• W3165547188 hasConcept C2781066024 @default.
• W3165547188 hasConcept C2781076698 @default.
• W3165547188 hasConcept C2781463628 @default.
• W3165547188 hasConcept C40875361 @default.
• W3165547188 hasConcept C50027330 @default.
• W3165547188 hasConcept C506198293 @default.
• W3165547188 hasConcept C9061509 @default.
• W3165547188 hasConceptScore W3165547188C108204754 @default.
• W3165547188 hasConceptScore W3165547188C135731615 @default.
• W3165547188 hasConceptScore W3165547188C145148216 @default.
• W3165547188 hasConceptScore W3165547188C155647269 @default.
• W3165547188 hasConceptScore W3165547188C161790260 @default.
• W3165547188 hasConceptScore W3165547188C178790620 @default.
• W3165547188 hasConceptScore W3165547188C178907741 @default.
• W3165547188 hasConceptScore W3165547188C179104552 @default.
• W3165547188 hasConceptScore W3165547188C185592680 @default.
• W3165547188 hasConceptScore W3165547188C2778689049 @default.
• W3165547188 hasConceptScore W3165547188C2780263894 @default.
• W3165547188 hasConceptScore W3165547188C2780471494 @default.

• next