FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165647572> ?p ?o ?g. }

• W3165647572 endingPage "4673" @default.
• W3165647572 startingPage "4663" @default.
• W3165647572 abstract "The recent Zika virus (ZIKV) epidemic poses a serious threat to global health due to its association with microcephaly and congenital diseases in newborns and neurological complications and Guillain-Barré syndrome in adults. However, the majority of people infected with ZIKV do not develop symptoms. The platforms aimed to specifically diagnose ZIKV infection are needed for patient care and public health surveillance. In the study, four ZIKV envelope (E) protein-specific monoclonal antibodies (mAbs) (A1, B1, C1, and 9E-1) have been developed by using the conventional mAb technology. The binding epitopes of mAbs A1, B1, C1, and 9E-1 are located at E(238-257), E(410-431), E(258-277), and E(340-356), respectively. mAb 9E-1 performs 1.4- to 47-fold strong affinity to ZIKV E protein compared to another three mAbs. mAbs A1, C1, and 9E-1 do not have cross-reactivity against the recombinant E proteins of dengue virus serotypes 2, 3, and 4. Although these four mAbs do not have ZIKV neutralizing activity, mAbs B1 and 9E-1 have been developed as the lateral flow immunochromatographic assay for specific detection of ZIKV E protein and virions. KEY POINTS: • The mAbs targeting to the regions of E(238-257), E(410-431), E(258-277), and E(340-356) do not have ZIKV neutralizing activity. • The binding epitope of mAb 9E-1 is highly specific to ZIKV E protein. • mAbs B1 and 9E-1 can bind to ZIKV virions and have been developed as the lateral flow immunochromatographic assay." @default.
• W3165647572 created "2021-06-07" @default.
• W3165647572 creator A5007605702 @default.
• W3165647572 creator A5038102613 @default.
• W3165647572 creator A5071838449 @default.
• W3165647572 creator A5088155237 @default.
• W3165647572 date "2021-05-27" @default.
• W3165647572 modified "2023-09-26" @default.
• W3165647572 title "Development and characterization of mouse monoclonal antibodies targeting to distinct epitopes of Zika virus envelope protein for specific detection of Zika virus" @default.
• W3165647572 cites W1545235721 @default.
• W3165647572 cites W1974965086 @default.
• W3165647572 cites W2060303925 @default.
• W3165647572 cites W2087491932 @default.
• W3165647572 cites W2091789910 @default.
• W3165647572 cites W2128635872 @default.
• W3165647572 cites W2132898662 @default.
• W3165647572 cites W2288668982 @default.
• W3165647572 cites W2292786359 @default.
• W3165647572 cites W2460107925 @default.
• W3165647572 cites W2464735068 @default.
• W3165647572 cites W2469258508 @default.
• W3165647572 cites W2485191472 @default.
• W3165647572 cites W2493146871 @default.
• W3165647572 cites W2552383104 @default.
• W3165647572 cites W2726244132 @default.
• W3165647572 cites W2758691957 @default.
• W3165647572 cites W2792368534 @default.
• W3165647572 cites W2894723361 @default.
• W3165647572 cites W2900452554 @default.
• W3165647572 cites W2904937055 @default.
• W3165647572 cites W2925123003 @default.
• W3165647572 cites W3004159088 @default.
• W3165647572 cites W3108386047 @default.
• W3165647572 cites W3139182354 @default.
• W3165647572 cites W4210756053 @default.
• W3165647572 cites W4293247451 @default.
• W3165647572 doi "https://doi.org/10.1007/s00253-021-11364-1" @default.
• W3165647572 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8156580" @default.
• W3165647572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34043078" @default.
• W3165647572 hasPublicationYear "2021" @default.
• W3165647572 type Work @default.
• W3165647572 sameAs 3165647572 @default.
• W3165647572 citedByCount "7" @default.
• W3165647572 countsByYear W31656475722021 @default.
• W3165647572 countsByYear W31656475722022 @default.
• W3165647572 countsByYear W31656475722023 @default.
• W3165647572 crossrefType "journal-article" @default.
• W3165647572 hasAuthorship W3165647572A5007605702 @default.
• W3165647572 hasAuthorship W3165647572A5038102613 @default.
• W3165647572 hasAuthorship W3165647572A5071838449 @default.
• W3165647572 hasAuthorship W3165647572A5088155237 @default.
• W3165647572 hasBestOaLocation W31656475721 @default.
• W3165647572 hasConcept C104317684 @default.
• W3165647572 hasConcept C159047783 @default.
• W3165647572 hasConcept C159654299 @default.
• W3165647572 hasConcept C195616568 @default.
• W3165647572 hasConcept C203014093 @default.
• W3165647572 hasConcept C2522874641 @default.
• W3165647572 hasConcept C2776395126 @default.
• W3165647572 hasConcept C2777053367 @default.
• W3165647572 hasConcept C2779635636 @default.
• W3165647572 hasConcept C2781241564 @default.
• W3165647572 hasConcept C40767141 @default.
• W3165647572 hasConcept C542903549 @default.
• W3165647572 hasConcept C54355233 @default.
• W3165647572 hasConcept C55493867 @default.
• W3165647572 hasConcept C86803240 @default.
• W3165647572 hasConceptScore W3165647572C104317684 @default.
• W3165647572 hasConceptScore W3165647572C159047783 @default.
• W3165647572 hasConceptScore W3165647572C159654299 @default.
• W3165647572 hasConceptScore W3165647572C195616568 @default.
• W3165647572 hasConceptScore W3165647572C203014093 @default.
• W3165647572 hasConceptScore W3165647572C2522874641 @default.
• W3165647572 hasConceptScore W3165647572C2776395126 @default.
• W3165647572 hasConceptScore W3165647572C2777053367 @default.
• W3165647572 hasConceptScore W3165647572C2779635636 @default.
• W3165647572 hasConceptScore W3165647572C2781241564 @default.
• W3165647572 hasConceptScore W3165647572C40767141 @default.
• W3165647572 hasConceptScore W3165647572C542903549 @default.
• W3165647572 hasConceptScore W3165647572C54355233 @default.
• W3165647572 hasConceptScore W3165647572C55493867 @default.
• W3165647572 hasConceptScore W3165647572C86803240 @default.
• W3165647572 hasFunder F4320322795 @default.
• W3165647572 hasFunder F4320323900 @default.
• W3165647572 hasIssue "11" @default.
• W3165647572 hasLocation W31656475721 @default.
• W3165647572 hasLocation W31656475722 @default.
• W3165647572 hasLocation W31656475723 @default.
• W3165647572 hasOpenAccess W3165647572 @default.
• W3165647572 hasPrimaryLocation W31656475721 @default.
• W3165647572 hasRelatedWork W1679554208 @default.
• W3165647572 hasRelatedWork W2039736738 @default.
• W3165647572 hasRelatedWork W2060284918 @default.
• W3165647572 hasRelatedWork W2101355465 @default.
• W3165647572 hasRelatedWork W2119878731 @default.
• W3165647572 hasRelatedWork W2565798303 @default.
• W3165647572 hasRelatedWork W2762381237 @default.
• W3165647572 hasRelatedWork W2945482808 @default.

• next