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- W3165730553 abstract "Abstract Tissue engineering is a systematic approach of assembling cells onto a 3D scaffold to form a functional tissue in the presence of critical growth factors. The scaffolding system guides stem cells through topological, physiochemical, and mechanical cues to differentiate and integrate to form a functional tissue. However, cellular communication during tissue formation taking place in a reactor needs to be understood properly to enable appropriate positioning of the cells in a 3D environment. Hence, sensors and actuators integrated with cyber‐physical system (CPS) may be able to sense the tissue microenvironment and direct cells/cellular aggregates to an appropriate position, respectively. This can facilitate better cell‐to‐cell communication and cell–extracellular matrix communication for proper tissue morphogenesis. Advancements are made in the field of smart scaffolds that can morph cells/cellular aggregates after sensing the cellular microenvironment in a desired 3D architecture by providing appropriate cues. Recent scientific developments in the additive manufacturing technology have enabled the fabrication of smart scaffolds to create structural and functional tissue constructs. Sensors/actuators, cyber‐systems, smart materials, and additive manufacturing put together is expected to lead to improved tissue‐engineered medical products. The present review aims to highlight the possibilities of advancement of BioCPS for tissue engineering and regenerative medicine." @default.
- W3165730553 created "2021-06-07" @default.
- W3165730553 creator A5012773666 @default.
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- W3165730553 creator A5036138960 @default.
- W3165730553 creator A5056594389 @default.
- W3165730553 creator A5066655760 @default.
- W3165730553 date "2021-05-24" @default.
- W3165730553 modified "2023-10-14" @default.
- W3165730553 title "Tissue Regeneration through Cyber‐Physical Systems and Microbots" @default.
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