Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165850135> ?p ?o ?g. }
- W3165850135 abstract "In healthy young volunteers, acquisition of blood oxygen level-dependent (BOLD) magnetic resonance (MR) and muscle sympathetic nerve (MSNA) signals during simulation of obstructive or central sleep apnea identified cortical cardiovascular autonomic regions in which the BOLD signal changed synchronously with acute noradrenergic excitation. In the present work, we tested the hypothesis that such Mueller maneuvers (MM) and breath-holds (BH) would elicit greater concomitant changes in mean efferent nerve firing and BOLD signal intensity in patients with moderate to severe obstructive sleep apnea (OSA) relative to age- and sex-matched individuals with no or only mild OSA (Apnea Hypopnea Index, AHI, <15 events/h). Forty-six participants, 24 with OSA [59 ± 8 years; AHI 31 ± 18 events/h (mean ± SD); seven women] and 22 without (58 ± 11 years; AHI 7 ± 4; nine women), performed a series of three MM and three BH, in randomly assigned order, twice: during continuous recording of MSNA from the right fibular nerve and, on a separate day, during T2 ∗ -weighted echo planar functional MR imaging. MSNA at rest was greater in those with OSA (65 ± 19 vs. 48 ± 17 bursts per 100 heart beats; p < 0.01). MM and BH elicited similar heart rate, blood pressure, and MSNA responses in the two cohorts; group mean BOLD data were concordant, detecting no between-group differences in cortical autonomic region signal activities. The present findings do not support the concept that recurring episodes of cyclical apnea during sleep alter cortical or peripheral neural responsiveness to their simulation during wakefulness by volitional Mueller maneuvers or breath-holds." @default.
- W3165850135 created "2021-06-07" @default.
- W3165850135 creator A5000907035 @default.
- W3165850135 creator A5008290804 @default.
- W3165850135 creator A5012715198 @default.
- W3165850135 creator A5031368351 @default.
- W3165850135 creator A5043046036 @default.
- W3165850135 creator A5048226129 @default.
- W3165850135 creator A5050832519 @default.
- W3165850135 date "2021-05-26" @default.
- W3165850135 modified "2023-09-25" @default.
- W3165850135 title "Comparison of Cortical Autonomic Network-Linked Sympathetic Excitation by Mueller Maneuvers and Breath-Holds in Subjects With and Without Obstructive Sleep Apnea" @default.
- W3165850135 cites W131615448 @default.
- W3165850135 cites W1852307386 @default.
- W3165850135 cites W1964530016 @default.
- W3165850135 cites W1998146296 @default.
- W3165850135 cites W2008889166 @default.
- W3165850135 cites W2015684179 @default.
- W3165850135 cites W2047620989 @default.
- W3165850135 cites W2059982399 @default.
- W3165850135 cites W2071714163 @default.
- W3165850135 cites W2088119533 @default.
- W3165850135 cites W2109586252 @default.
- W3165850135 cites W2122938717 @default.
- W3165850135 cites W2140058549 @default.
- W3165850135 cites W2144119091 @default.
- W3165850135 cites W2149754624 @default.
- W3165850135 cites W2150696106 @default.
- W3165850135 cites W2162279658 @default.
- W3165850135 cites W2264784497 @default.
- W3165850135 cites W2490953130 @default.
- W3165850135 cites W2511175036 @default.
- W3165850135 cites W2528548673 @default.
- W3165850135 cites W2573476440 @default.
- W3165850135 cites W2779102666 @default.
- W3165850135 cites W2805115566 @default.
- W3165850135 cites W2882999799 @default.
- W3165850135 cites W2946415755 @default.
- W3165850135 cites W2969332313 @default.
- W3165850135 cites W4236639771 @default.
- W3165850135 cites W4246370350 @default.
- W3165850135 doi "https://doi.org/10.3389/fphys.2021.678630" @default.
- W3165850135 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8188800" @default.
- W3165850135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34122146" @default.
- W3165850135 hasPublicationYear "2021" @default.
- W3165850135 type Work @default.
- W3165850135 sameAs 3165850135 @default.
- W3165850135 citedByCount "3" @default.
- W3165850135 countsByYear W31658501352022 @default.
- W3165850135 countsByYear W31658501352023 @default.
- W3165850135 crossrefType "journal-article" @default.
- W3165850135 hasAuthorship W3165850135A5000907035 @default.
- W3165850135 hasAuthorship W3165850135A5008290804 @default.
- W3165850135 hasAuthorship W3165850135A5012715198 @default.
- W3165850135 hasAuthorship W3165850135A5031368351 @default.
- W3165850135 hasAuthorship W3165850135A5043046036 @default.
- W3165850135 hasAuthorship W3165850135A5048226129 @default.
- W3165850135 hasAuthorship W3165850135A5050832519 @default.
- W3165850135 hasBestOaLocation W31658501351 @default.
- W3165850135 hasConcept C126322002 @default.
- W3165850135 hasConcept C164705383 @default.
- W3165850135 hasConcept C191237925 @default.
- W3165850135 hasConcept C2775898464 @default.
- W3165850135 hasConcept C2776006263 @default.
- W3165850135 hasConcept C2776512019 @default.
- W3165850135 hasConcept C2777372248 @default.
- W3165850135 hasConcept C2777935920 @default.
- W3165850135 hasConcept C2777953023 @default.
- W3165850135 hasConcept C2779263132 @default.
- W3165850135 hasConcept C2781326671 @default.
- W3165850135 hasConcept C42219234 @default.
- W3165850135 hasConcept C71924100 @default.
- W3165850135 hasConcept C84393581 @default.
- W3165850135 hasConceptScore W3165850135C126322002 @default.
- W3165850135 hasConceptScore W3165850135C164705383 @default.
- W3165850135 hasConceptScore W3165850135C191237925 @default.
- W3165850135 hasConceptScore W3165850135C2775898464 @default.
- W3165850135 hasConceptScore W3165850135C2776006263 @default.
- W3165850135 hasConceptScore W3165850135C2776512019 @default.
- W3165850135 hasConceptScore W3165850135C2777372248 @default.
- W3165850135 hasConceptScore W3165850135C2777935920 @default.
- W3165850135 hasConceptScore W3165850135C2777953023 @default.
- W3165850135 hasConceptScore W3165850135C2779263132 @default.
- W3165850135 hasConceptScore W3165850135C2781326671 @default.
- W3165850135 hasConceptScore W3165850135C42219234 @default.
- W3165850135 hasConceptScore W3165850135C71924100 @default.
- W3165850135 hasConceptScore W3165850135C84393581 @default.
- W3165850135 hasFunder F4320319963 @default.
- W3165850135 hasLocation W31658501351 @default.
- W3165850135 hasLocation W31658501352 @default.
- W3165850135 hasOpenAccess W3165850135 @default.
- W3165850135 hasPrimaryLocation W31658501351 @default.
- W3165850135 hasRelatedWork W2012930788 @default.
- W3165850135 hasRelatedWork W2031046801 @default.
- W3165850135 hasRelatedWork W2076040967 @default.
- W3165850135 hasRelatedWork W2319407515 @default.
- W3165850135 hasRelatedWork W2366584003 @default.
- W3165850135 hasRelatedWork W2379268248 @default.
- W3165850135 hasRelatedWork W2914433975 @default.
- W3165850135 hasRelatedWork W3086894951 @default.