FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3165851052> ?p ?o ?g. }

• W3165851052 endingPage "104249" @default.
• W3165851052 startingPage "104249" @default.
• W3165851052 abstract "Inherited liver diseases may present in infancy as cholestatic jaundice progressing to severe hepatic dysfunction. Congenital cytomegalovirus (cCMV) infection may initially involve the liver, yet in otherwise healthy hosts rarely leads to long-term hepatic disease. We report a series of three patients, diagnosed with hereditary liver diseases: progressive familial intrahepatic cholestasis (PFIC) type IV, alpha 1 anti-trypsin deficiency (A1ATD) and Alagille syndrome (ALGS), who were also diagnosed with cCMV infection. All patients were treated with valgancilovir for symptomatic cCMV infection (6–12 months), followed by suppressive dosing in the 2 patients with PFIC and A1ATD. Following 15–24 months of follow-up – the patients with PFIC and A1ATD developed severe liver failure, and the third had ongoing cholestatic disease with stable synthetic function. We propose a significant contribution of cCMV infection to the course of the inherited primary disease, possibly leading to further compromise of the liver. We recommend screening patients with inherited liver disease for cCMV, and considering anti-viral treatment with valganciclovir to delay hepatic disease progression." @default.
• W3165851052 created "2021-06-07" @default.
• W3165851052 creator A5008330953 @default.
• W3165851052 creator A5017756474 @default.
• W3165851052 creator A5020697946 @default.
• W3165851052 creator A5023371777 @default.
• W3165851052 creator A5024873665 @default.
• W3165851052 creator A5031387182 @default.
• W3165851052 creator A5046628932 @default.
• W3165851052 creator A5050315219 @default.
• W3165851052 date "2021-08-01" @default.
• W3165851052 modified "2023-09-25" @default.
• W3165851052 title "Concomitant congenital CMV infection and inherited liver diseases" @default.
• W3165851052 cites W1964727784 @default.
• W3165851052 cites W2003053851 @default.
• W3165851052 cites W2020955986 @default.
• W3165851052 cites W2037566373 @default.
• W3165851052 cites W2038473893 @default.
• W3165851052 cites W2056386643 @default.
• W3165851052 cites W2081325661 @default.
• W3165851052 cites W2085800014 @default.
• W3165851052 cites W2143495274 @default.
• W3165851052 cites W2144052741 @default.
• W3165851052 cites W2607437541 @default.
• W3165851052 cites W2732595525 @default.
• W3165851052 cites W2740249807 @default.
• W3165851052 cites W2907576011 @default.
• W3165851052 cites W2945827071 @default.
• W3165851052 cites W3096214547 @default.
• W3165851052 cites W4233892901 @default.
• W3165851052 doi "https://doi.org/10.1016/j.ejmg.2021.104249" @default.
• W3165851052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34023521" @default.
• W3165851052 hasPublicationYear "2021" @default.
• W3165851052 type Work @default.
• W3165851052 sameAs 3165851052 @default.
• W3165851052 citedByCount "2" @default.
• W3165851052 countsByYear W31658510522022 @default.
• W3165851052 crossrefType "journal-article" @default.
• W3165851052 hasAuthorship W3165851052A5008330953 @default.
• W3165851052 hasAuthorship W3165851052A5017756474 @default.
• W3165851052 hasAuthorship W3165851052A5020697946 @default.
• W3165851052 hasAuthorship W3165851052A5023371777 @default.
• W3165851052 hasAuthorship W3165851052A5024873665 @default.
• W3165851052 hasAuthorship W3165851052A5031387182 @default.
• W3165851052 hasAuthorship W3165851052A5046628932 @default.
• W3165851052 hasAuthorship W3165851052A5050315219 @default.
• W3165851052 hasConcept C126322002 @default.
• W3165851052 hasConcept C203014093 @default.
• W3165851052 hasConcept C2522874641 @default.
• W3165851052 hasConcept C2776317777 @default.
• W3165851052 hasConcept C2776409557 @default.
• W3165851052 hasConcept C2777075537 @default.
• W3165851052 hasConcept C2777732132 @default.
• W3165851052 hasConcept C2777965375 @default.
• W3165851052 hasConcept C2778132995 @default.
• W3165851052 hasConcept C2778456037 @default.
• W3165851052 hasConcept C2778593092 @default.
• W3165851052 hasConcept C2779609443 @default.
• W3165851052 hasConcept C2779820661 @default.
• W3165851052 hasConcept C2780727368 @default.
• W3165851052 hasConcept C2911091166 @default.
• W3165851052 hasConcept C71924100 @default.
• W3165851052 hasConcept C90924648 @default.
• W3165851052 hasConceptScore W3165851052C126322002 @default.
• W3165851052 hasConceptScore W3165851052C203014093 @default.
• W3165851052 hasConceptScore W3165851052C2522874641 @default.
• W3165851052 hasConceptScore W3165851052C2776317777 @default.
• W3165851052 hasConceptScore W3165851052C2776409557 @default.
• W3165851052 hasConceptScore W3165851052C2777075537 @default.
• W3165851052 hasConceptScore W3165851052C2777732132 @default.
• W3165851052 hasConceptScore W3165851052C2777965375 @default.
• W3165851052 hasConceptScore W3165851052C2778132995 @default.
• W3165851052 hasConceptScore W3165851052C2778456037 @default.
• W3165851052 hasConceptScore W3165851052C2778593092 @default.
• W3165851052 hasConceptScore W3165851052C2779609443 @default.
• W3165851052 hasConceptScore W3165851052C2779820661 @default.
• W3165851052 hasConceptScore W3165851052C2780727368 @default.
• W3165851052 hasConceptScore W3165851052C2911091166 @default.
• W3165851052 hasConceptScore W3165851052C71924100 @default.
• W3165851052 hasConceptScore W3165851052C90924648 @default.
• W3165851052 hasIssue "8" @default.
• W3165851052 hasLocation W31658510521 @default.
• W3165851052 hasOpenAccess W3165851052 @default.
• W3165851052 hasPrimaryLocation W31658510521 @default.
• W3165851052 hasRelatedWork W2020955986 @default.
• W3165851052 hasRelatedWork W2028683799 @default.
• W3165851052 hasRelatedWork W2163637001 @default.
• W3165851052 hasRelatedWork W2183678977 @default.
• W3165851052 hasRelatedWork W2467711019 @default.
• W3165851052 hasRelatedWork W2473296006 @default.
• W3165851052 hasRelatedWork W2559945960 @default.
• W3165851052 hasRelatedWork W2945281647 @default.
• W3165851052 hasRelatedWork W3044537086 @default.
• W3165851052 hasRelatedWork W3165851052 @default.
• W3165851052 hasVolume "64" @default.
• W3165851052 isParatext "false" @default.
• W3165851052 isRetracted "false" @default.
• W3165851052 magId "3165851052" @default.

• next