Matches in SemOpenAlex for { <https://semopenalex.org/work/W3166322182> ?p ?o ?g. }
- W3166322182 endingPage "112347" @default.
- W3166322182 startingPage "112347" @default.
- W3166322182 abstract "Aluminum phosphide (AlP) causes severe cardiotoxicity. Taurine has been chosen for the present study because of its positive known effects on cardiac injuries.To evaluate AlP-induced cardiotoxicity, the animals were divided into seven groups, including the control group, the taurine group (500 mg/kg), AlP with LD50 dose, AlP + taurine 20, 50, 100, and 200 mg/kg group. To assess cardiac hemodynamic parameters, Wistar rats received taurine intraperitoneally 60 min after AlP gavage. Cardiac hemodynamic parameters were evaluated for 180 min. To study biochemical parameters, 24 h after AlP treatment, the animals were sacrificed, and heart tissues were collected.ECG, BP, and HR abnormalities of AlP poisoning were improved by taurine treatment. AlP induced biochemical alterations including complexes I and IV activities, the ADP/ATP ratio, mitochondrial membrane potential, cytochrome C release, and oxidative stress biomarkers ameliorated by taurine. Moreover, taurine improved apoptosis, as well as lessened CK-MB and troponin I levels. Also, there were no significant changes between taurine 500 mg/kg and the control group in tests.The present findings showed that taurine could be a possible candidate for AlP cardiotoxicity treatment via the effect on mitochondrial electron transfer chain and maintaining intracellular ATP balance." @default.
- W3166322182 created "2021-06-22" @default.
- W3166322182 creator A5000338563 @default.
- W3166322182 creator A5001005609 @default.
- W3166322182 creator A5011956874 @default.
- W3166322182 creator A5012518208 @default.
- W3166322182 creator A5015354186 @default.
- W3166322182 creator A5017149601 @default.
- W3166322182 creator A5018770850 @default.
- W3166322182 creator A5024329578 @default.
- W3166322182 creator A5035375081 @default.
- W3166322182 creator A5035795673 @default.
- W3166322182 creator A5045614706 @default.
- W3166322182 creator A5068985799 @default.
- W3166322182 creator A5072119690 @default.
- W3166322182 date "2021-08-01" @default.
- W3166322182 modified "2023-10-18" @default.
- W3166322182 title "On the mechanisms of taurine in alleviating electrocardiographic, hemodynamic, and biochemical parameters following aluminum phosphide cardiotoxicity" @default.
- W3166322182 cites W170230243 @default.
- W3166322182 cites W1899446742 @default.
- W3166322182 cites W1923644994 @default.
- W3166322182 cites W1965156176 @default.
- W3166322182 cites W1973244492 @default.
- W3166322182 cites W1974650485 @default.
- W3166322182 cites W1989577097 @default.
- W3166322182 cites W2021195693 @default.
- W3166322182 cites W2024886796 @default.
- W3166322182 cites W2029162976 @default.
- W3166322182 cites W2039192668 @default.
- W3166322182 cites W2045024343 @default.
- W3166322182 cites W2056481528 @default.
- W3166322182 cites W2058888796 @default.
- W3166322182 cites W2085015578 @default.
- W3166322182 cites W2089923455 @default.
- W3166322182 cites W2091791488 @default.
- W3166322182 cites W2092862331 @default.
- W3166322182 cites W2101385273 @default.
- W3166322182 cites W2126038714 @default.
- W3166322182 cites W2135462156 @default.
- W3166322182 cites W2141478909 @default.
- W3166322182 cites W2167143237 @default.
- W3166322182 cites W2219054018 @default.
- W3166322182 cites W2403445405 @default.
- W3166322182 cites W2554066469 @default.
- W3166322182 cites W2563793913 @default.
- W3166322182 cites W2581249347 @default.
- W3166322182 cites W2619501332 @default.
- W3166322182 cites W2620387517 @default.
- W3166322182 cites W2735590725 @default.
- W3166322182 cites W2753006837 @default.
- W3166322182 cites W2793221189 @default.
- W3166322182 cites W2797730765 @default.
- W3166322182 cites W2799455014 @default.
- W3166322182 cites W2802928954 @default.
- W3166322182 cites W2805891492 @default.
- W3166322182 cites W2884902042 @default.
- W3166322182 cites W2887684432 @default.
- W3166322182 cites W2888818085 @default.
- W3166322182 cites W2894739452 @default.
- W3166322182 cites W2902173935 @default.
- W3166322182 cites W2954076272 @default.
- W3166322182 cites W2956010314 @default.
- W3166322182 cites W2959244275 @default.
- W3166322182 cites W2959467487 @default.
- W3166322182 cites W2976573226 @default.
- W3166322182 cites W2982320691 @default.
- W3166322182 cites W2996101552 @default.
- W3166322182 cites W3017323134 @default.
- W3166322182 cites W3035734257 @default.
- W3166322182 cites W3040406897 @default.
- W3166322182 cites W3049057008 @default.
- W3166322182 cites W3082429953 @default.
- W3166322182 cites W3085530647 @default.
- W3166322182 cites W3110672190 @default.
- W3166322182 cites W4293247451 @default.
- W3166322182 cites W955503740 @default.
- W3166322182 doi "https://doi.org/10.1016/j.fct.2021.112347" @default.
- W3166322182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34139304" @default.
- W3166322182 hasPublicationYear "2021" @default.
- W3166322182 type Work @default.
- W3166322182 sameAs 3166322182 @default.
- W3166322182 citedByCount "11" @default.
- W3166322182 countsByYear W31663221822021 @default.
- W3166322182 countsByYear W31663221822022 @default.
- W3166322182 countsByYear W31663221822023 @default.
- W3166322182 crossrefType "journal-article" @default.
- W3166322182 hasAuthorship W3166322182A5000338563 @default.
- W3166322182 hasAuthorship W3166322182A5001005609 @default.
- W3166322182 hasAuthorship W3166322182A5011956874 @default.
- W3166322182 hasAuthorship W3166322182A5012518208 @default.
- W3166322182 hasAuthorship W3166322182A5015354186 @default.
- W3166322182 hasAuthorship W3166322182A5017149601 @default.
- W3166322182 hasAuthorship W3166322182A5018770850 @default.
- W3166322182 hasAuthorship W3166322182A5024329578 @default.
- W3166322182 hasAuthorship W3166322182A5035375081 @default.
- W3166322182 hasAuthorship W3166322182A5035795673 @default.
- W3166322182 hasAuthorship W3166322182A5045614706 @default.
- W3166322182 hasAuthorship W3166322182A5068985799 @default.