FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167014905> ?p ?o ?g. }

• W3167014905 abstract "Abstract Introduction The dynamic nature and complexity of the cellular events that take place during the last trimester of pregnancy make the developing cortex particularly vulnerable to perturbations. Abrupt interruption to normal gestation can lead to significant deviations to many of these processes, resulting in atypical trajectory of cortical maturation in preterm birth survivors. Methods We sought to first map typical cortical micro and macrostructure development using invivo MRI in a large sample of healthy term-born infants scanned after birth (n=270). Then we offer a comprehensive characterisation of the cortical consequences of preterm birth in 78 preterm infants scanned at term-equivalent age (37-44 weeks postmenstrual age). We describe the group-average atypicality, the heterogeneity across individual preterm infants, and relate individual deviations from normative development to age at birth and neurodevelopment at 18 months. Results In the term-born neonatal brain, we observed regionally specific age-associated changes in cortical morphology and microstructure, including rapid surface expansion, cortical thickness increase, reduction in cortical anisotropy and increase in neurite orientation dispersion. By term-equivalent age, preterm infants had on average increased cortical tissue water content and reduced neurite density index in the posterior parts of the cortex, and greater cortical thickness anteriorly compared to term-born infants. While individual preterm infants were more likely to show extreme deviations (over 3.1 standard deviations) from normative cortical maturation compared to term-born infants, these extreme deviations were highly variable and showed very little spatial overlap between individuals. Measures of regional cortical development were associated with age at birth, but not with neurodevelopment at 18 months. Conclusion We showed that preterm birth alters cortical micro and macrostructural maturation near the time of fullterm birth. Deviations from normative development were highly variable between individual preterm infants." @default.
• W3167014905 created "2021-06-22" @default.
• W3167014905 creator A5002029680 @default.
• W3167014905 creator A5002812780 @default.
• W3167014905 creator A5006461848 @default.
• W3167014905 creator A5007221038 @default.
• W3167014905 creator A5007821573 @default.
• W3167014905 creator A5010565192 @default.
• W3167014905 creator A5011549928 @default.
• W3167014905 creator A5030767422 @default.
• W3167014905 creator A5031524161 @default.
• W3167014905 creator A5035958199 @default.
• W3167014905 creator A5043671632 @default.
• W3167014905 creator A5045624234 @default.
• W3167014905 creator A5053114506 @default.
• W3167014905 creator A5053901484 @default.
• W3167014905 creator A5054723681 @default.
• W3167014905 creator A5055150304 @default.
• W3167014905 creator A5055261845 @default.
• W3167014905 creator A5057304825 @default.
• W3167014905 creator A5068281609 @default.
• W3167014905 creator A5072116435 @default.
• W3167014905 creator A5073683894 @default.
• W3167014905 creator A5077183208 @default.
• W3167014905 creator A5082377236 @default.
• W3167014905 creator A5083630655 @default.
• W3167014905 creator A5084126057 @default.
• W3167014905 creator A5087809109 @default.
• W3167014905 creator A5091185185 @default.
• W3167014905 date "2021-06-03" @default.
• W3167014905 modified "2023-10-16" @default.
• W3167014905 title "Preterm birth alters the development of cortical microstructure and morphology at term-equivalent age" @default.
• W3167014905 cites W1497967188 @default.
• W3167014905 cites W1864343960 @default.
• W3167014905 cites W1965092590 @default.
• W3167014905 cites W1975192282 @default.
• W3167014905 cites W1982912347 @default.
• W3167014905 cites W1984453610 @default.
• W3167014905 cites W1990497177 @default.
• W3167014905 cites W1994593704 @default.
• W3167014905 cites W1995430838 @default.
• W3167014905 cites W1998454877 @default.
• W3167014905 cites W2000193800 @default.
• W3167014905 cites W2004006028 @default.
• W3167014905 cites W2007500561 @default.
• W3167014905 cites W2008564181 @default.
• W3167014905 cites W2014835131 @default.
• W3167014905 cites W2016693709 @default.
• W3167014905 cites W2030216510 @default.
• W3167014905 cites W2032254014 @default.
• W3167014905 cites W2041706109 @default.
• W3167014905 cites W2044947593 @default.
• W3167014905 cites W2052644075 @default.
• W3167014905 cites W2063010771 @default.
• W3167014905 cites W2065835984 @default.
• W3167014905 cites W2073588997 @default.
• W3167014905 cites W2075761659 @default.
• W3167014905 cites W2076605578 @default.
• W3167014905 cites W2077667106 @default.
• W3167014905 cites W2079141380 @default.
• W3167014905 cites W2083193505 @default.
• W3167014905 cites W2087642535 @default.
• W3167014905 cites W2097133042 @default.
• W3167014905 cites W2105549490 @default.
• W3167014905 cites W2111884236 @default.
• W3167014905 cites W2115994811 @default.
• W3167014905 cites W2117987496 @default.
• W3167014905 cites W2118779149 @default.
• W3167014905 cites W2118802114 @default.
• W3167014905 cites W2126693856 @default.
• W3167014905 cites W2142932869 @default.
• W3167014905 cites W2151636191 @default.
• W3167014905 cites W2152294954 @default.
• W3167014905 cites W2152444032 @default.
• W3167014905 cites W2177835590 @default.
• W3167014905 cites W2217049202 @default.
• W3167014905 cites W2229782077 @default.
• W3167014905 cites W2319887059 @default.
• W3167014905 cites W2323667057 @default.
• W3167014905 cites W2507387536 @default.
• W3167014905 cites W2508982726 @default.
• W3167014905 cites W2524545577 @default.
• W3167014905 cites W2529762510 @default.
• W3167014905 cites W2587717914 @default.
• W3167014905 cites W2620379761 @default.
• W3167014905 cites W2626006036 @default.
• W3167014905 cites W2743872579 @default.
• W3167014905 cites W2765121383 @default.
• W3167014905 cites W2768271247 @default.
• W3167014905 cites W2790008622 @default.
• W3167014905 cites W2792313030 @default.
• W3167014905 cites W2799932987 @default.
• W3167014905 cites W2804580576 @default.
• W3167014905 cites W2808621709 @default.
• W3167014905 cites W2808633052 @default.
• W3167014905 cites W2896481393 @default.
• W3167014905 cites W2915199536 @default.
• W3167014905 cites W2916365351 @default.
• W3167014905 cites W2951042025 @default.
• W3167014905 cites W2951533726 @default.

• next