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• W3167017852 abstract "OX40 is one of the co-stimulatory molecules expressed on T cells, and it is engaged by OX40L, primarily expressed on professional antigen-presenting cells such as dendritic cells. The OX40L–OX40 axis is involved in the sustained activation and expansion of effector T and effector memory T cells, but it is not active in naïve and resting memory T cells. Ligation of OX40 by OX40L accelerates both T helper 1 (Th1) and T helper 2 (Th2) effector cell differentiation. Recent therapeutic success in clinical trials highlights the importance of the OX40L–OX40 axis as a promising target for the treatment of atopic dermatitis." @default.
• W3167017852 created "2021-06-22" @default.
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• W3167017852 date "2021-06-11" @default.
• W3167017852 modified "2023-10-06" @default.
• W3167017852 title "OX40L–OX40 Signaling in Atopic Dermatitis" @default.
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• W3167017852 doi "https://doi.org/10.3390/jcm10122578" @default.
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