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- W3167232235 abstract "IPSC line RCPCMi004-8 was generated from skin fibroblasts collected from a male patient with spinocerebellar ataxia 17. The patient has expanded trinucleotide CAG repeats in the TBP (TATA-binding protein) gene on chromosome 6q27. The reprogramming of fibroblasts was performed with Sendai viruses containing Oct-4, Sox-2, Klf-4, and c-Myc. Pluripotency was confirmed by immunofluorescence, RT-PCR, and the formation of embryoid bodies. The RCPCMi008-A cell line carries the same trinucleotide CAG repeats in the TBP gene. The RCPCMi008-A cell line can be used to model Spinocerebellar ataxia in vitro." @default.
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- W3167232235 date "2021-07-01" @default.
- W3167232235 modified "2023-10-10" @default.
- W3167232235 title "Generation of induced pluripotent stem cell line RCPCMi008-A derived from patient with spinocerebellar ataxia 17" @default.
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- W3167232235 doi "https://doi.org/10.1016/j.scr.2021.102431" @default.
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