FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167238766> ?p ?o ?g. }

• W3167238766 abstract "The programmed cell death – apoptosis plays an important role in the life of the nucleated cells. It is a vital component of different processes, like normal cell cycle, embryonic development, development and functioning of the immune system, etc.  There are at least two signalling pathways that lead to apoptosis of the nucleated cells – the extrinsic pathway of the apoptosis and the intrinsic pathway of the apoptosis. The extrinsic pathway of apoptosis begins outside a cell, when conditions in the extracellular environment determine that a cell must die. The intrinsic pathway of apoptosis begins when an injury occurs within the cell and the resulting stress activates the apoptotic pathway. Erythrocytes, like nucleated cells, may undergo a form of suicidal cell death called eryptosis.  The fact is that erythrocytes, which are devoid of nuclei, contain most components of the receptor-dependent apoptotic pathway. The components of the extrinsic and intrinsic apoptotic pathways play a significant role at the different stages of erythropoiesis and even in mature erythrocytes. Mature erythrocytes contain most components of the receptor-dependent apoptotic pathway, however, common inducers of apoptosis do not activate this pathway.  Studies based on an animal model suggested that other stimuli, such as ROS or cholesterol accumulation, could activate the extrinsic apoptotic pathway. The data also demonstrate important effects of caspases-8 and caspase-3 on red cell membrane and membrane skeleton proteins, which are crucial in determining cell shape and erythrocyte deformability and therefore erythrocyte survival in the circulation. Understanding all of these processes may help to explain the pathophysiology of anemia. Despite extensive research, it is still unclear what the direct mechanism of apoptosis of erythroid cells is." @default.
• W3167238766 created "2021-06-22" @default.
• W3167238766 creator A5003431389 @default.
• W3167238766 creator A5035311506 @default.
• W3167238766 creator A5040366454 @default.
• W3167238766 creator A5079134475 @default.
• W3167238766 date "2021-05-25" @default.
• W3167238766 modified "2023-09-26" @default.
• W3167238766 title "THE COMPONENTS OF THE EXTRINSIC APOPTOTIC PATHWAY IN MATURE ERYTHROCYTES (BRIEF REVIEW)" @default.
• W3167238766 cites W113632086 @default.
• W3167238766 cites W1688650085 @default.
• W3167238766 cites W1977425342 @default.
• W3167238766 cites W1977852730 @default.
• W3167238766 cites W1980133784 @default.
• W3167238766 cites W1982936629 @default.
• W3167238766 cites W1984311540 @default.
• W3167238766 cites W1985560000 @default.
• W3167238766 cites W1994598048 @default.
• W3167238766 cites W2024548275 @default.
• W3167238766 cites W2027635465 @default.
• W3167238766 cites W2031809080 @default.
• W3167238766 cites W2043081908 @default.
• W3167238766 cites W2047558995 @default.
• W3167238766 cites W2048305330 @default.
• W3167238766 cites W2070480173 @default.
• W3167238766 cites W2072409837 @default.
• W3167238766 cites W2076273704 @default.
• W3167238766 cites W2077230219 @default.
• W3167238766 cites W2088533769 @default.
• W3167238766 cites W2094560153 @default.
• W3167238766 cites W2096188040 @default.
• W3167238766 cites W2107194336 @default.
• W3167238766 cites W2127883583 @default.
• W3167238766 cites W2165745548 @default.
• W3167238766 cites W2165979821 @default.
• W3167238766 cites W2317277068 @default.
• W3167238766 cites W2404042207 @default.
• W3167238766 cites W2781697521 @default.
• W3167238766 cites W2952380764 @default.
• W3167238766 cites W3087672831 @default.
• W3167238766 hasPublicationYear "2021" @default.
• W3167238766 type Work @default.
• W3167238766 sameAs 3167238766 @default.
• W3167238766 citedByCount "0" @default.
• W3167238766 crossrefType "journal-article" @default.
• W3167238766 hasAuthorship W3167238766A5003431389 @default.
• W3167238766 hasAuthorship W3167238766A5035311506 @default.
• W3167238766 hasAuthorship W3167238766A5040366454 @default.
• W3167238766 hasAuthorship W3167238766A5079134475 @default.
• W3167238766 hasConcept C104317684 @default.
• W3167238766 hasConcept C145103041 @default.
• W3167238766 hasConcept C1491633281 @default.
• W3167238766 hasConcept C163421366 @default.
• W3167238766 hasConcept C190283241 @default.
• W3167238766 hasConcept C31573885 @default.
• W3167238766 hasConcept C55493867 @default.
• W3167238766 hasConcept C62478195 @default.
• W3167238766 hasConcept C86803240 @default.
• W3167238766 hasConcept C95444343 @default.
• W3167238766 hasConcept C98424977 @default.
• W3167238766 hasConceptScore W3167238766C104317684 @default.
• W3167238766 hasConceptScore W3167238766C145103041 @default.
• W3167238766 hasConceptScore W3167238766C1491633281 @default.
• W3167238766 hasConceptScore W3167238766C163421366 @default.
• W3167238766 hasConceptScore W3167238766C190283241 @default.
• W3167238766 hasConceptScore W3167238766C31573885 @default.
• W3167238766 hasConceptScore W3167238766C55493867 @default.
• W3167238766 hasConceptScore W3167238766C62478195 @default.
• W3167238766 hasConceptScore W3167238766C86803240 @default.
• W3167238766 hasConceptScore W3167238766C95444343 @default.
• W3167238766 hasConceptScore W3167238766C98424977 @default.
• W3167238766 hasIssue "1" @default.
• W3167238766 hasLocation W31672387661 @default.
• W3167238766 hasOpenAccess W3167238766 @default.
• W3167238766 hasPrimaryLocation W31672387661 @default.
• W3167238766 hasRelatedWork W158576505 @default.
• W3167238766 hasRelatedWork W177850641 @default.
• W3167238766 hasRelatedWork W200014943 @default.
• W3167238766 hasRelatedWork W2004992894 @default.
• W3167238766 hasRelatedWork W2007612684 @default.
• W3167238766 hasRelatedWork W2090542705 @default.
• W3167238766 hasRelatedWork W2140894399 @default.
• W3167238766 hasRelatedWork W2230826446 @default.
• W3167238766 hasRelatedWork W2325279785 @default.
• W3167238766 hasRelatedWork W2412897950 @default.
• W3167238766 hasRelatedWork W2609843744 @default.
• W3167238766 hasRelatedWork W2890014969 @default.
• W3167238766 hasRelatedWork W2971153186 @default.
• W3167238766 hasRelatedWork W3041035815 @default.
• W3167238766 hasRelatedWork W3139411118 @default.
• W3167238766 hasRelatedWork W80745689 @default.
• W3167238766 hasRelatedWork W970399658 @default.
• W3167238766 hasRelatedWork W2337589602 @default.
• W3167238766 hasRelatedWork W2774689998 @default.
• W3167238766 hasRelatedWork W3118894527 @default.
• W3167238766 isParatext "false" @default.
• W3167238766 isRetracted "false" @default.
• W3167238766 magId "3167238766" @default.
• W3167238766 workType "article" @default.