Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167310167> ?p ?o ?g. }
- W3167310167 endingPage "109104" @default.
- W3167310167 startingPage "109104" @default.
- W3167310167 abstract "Bisphenol-A (BPA) is widely used in production of plastic products. It can reach the ecosystems affecting aquatic organisms most likely fishes. The purpose of this study was to study the toxic effects of BPA on the biochemical variables and oxidative stress in female African catfish, Clarias gariepinus and to estimate the protective role of chitosan nanoparticles (CSNPs) against BPA toxicity. Five groups in triplicates of fish were divided as follows: group I was control, group II was treated with CSNPs (0.66 ml/L), group III was exposed to BPA (1.43 μg/L), group IV was treated with BPA (1.43 μg/L) plus CSNPs (0.33 ml/L), and group V was treated with BPA (1.43 μg/L) plus CSNPs (0.66 ml/L) for 30 days. Blood and liver tissue samples were collected at the end of experiment for the biochemical and oxidative stress biomarkers analyses. Results exhibited that serum Follicle Stimulating Hormone (FSH) and 17-β Estradiol (E2) were significantly decreased in female catfish. While, serum Testosterone (T.) and Luteinizing Hormone (LH) were increased after exposure to BPA. Marked increment in superoxide dismutase (SOD) and malondialdehyde (MDA) levels of hepatic tissue of catfish exposed to BPA. Furthermore, significant reduction in hepatic catalase (CAT), glutathione peroxidase (GSH-px), total antioxidant capacity (TAC), reduced glutathione (GSH), and glutathione S-transferase (GST) levels were decreased significantly in BPA-exposed catfish compared to the control group. However, administration of female C. gariepinus with the low and high doses (0.33 ml/L and 0.66 ml/L) of CNPs restored the biochemical parameters to be close to the normal values of the control group and also, reduced oxidative stress induced by BPA toxicity. This improvement was evident in fish administrated with the high CSNPs dose (0.66 ml/L) compared to catfish exposed to BPA in group (III). Furthermore, the percentage of hepatic DNA damage was detected in group III exposed to BPA alone. However, it was declined after co- administration with both the low and high doses of CSNPs. The study has revealed that treatment with CSNPs has antagonistic functions against the toxicity of BPA in female African catfish." @default.
- W3167310167 created "2021-06-22" @default.
- W3167310167 creator A5015012931 @default.
- W3167310167 creator A5015633396 @default.
- W3167310167 creator A5035090908 @default.
- W3167310167 creator A5052039809 @default.
- W3167310167 date "2021-10-01" @default.
- W3167310167 modified "2023-09-23" @default.
- W3167310167 title "Chitosan nanoparticles alleviated endocrine disruption, oxidative damage, and genotoxicity of Bisphenol-A- intoxicated female African catfish" @default.
- W3167310167 cites W1581414347 @default.
- W3167310167 cites W191793640 @default.
- W3167310167 cites W1972129160 @default.
- W3167310167 cites W1976755375 @default.
- W3167310167 cites W1978138579 @default.
- W3167310167 cites W1983810285 @default.
- W3167310167 cites W1984685836 @default.
- W3167310167 cites W1985827317 @default.
- W3167310167 cites W1991775006 @default.
- W3167310167 cites W1992025440 @default.
- W3167310167 cites W1994417153 @default.
- W3167310167 cites W2006678816 @default.
- W3167310167 cites W2007888807 @default.
- W3167310167 cites W2011885764 @default.
- W3167310167 cites W2016049568 @default.
- W3167310167 cites W2017936668 @default.
- W3167310167 cites W2019387766 @default.
- W3167310167 cites W2022023971 @default.
- W3167310167 cites W2031258952 @default.
- W3167310167 cites W2036106922 @default.
- W3167310167 cites W2053054955 @default.
- W3167310167 cites W2058514558 @default.
- W3167310167 cites W2059218331 @default.
- W3167310167 cites W2060770480 @default.
- W3167310167 cites W2063131402 @default.
- W3167310167 cites W2080671154 @default.
- W3167310167 cites W2094399642 @default.
- W3167310167 cites W2095940090 @default.
- W3167310167 cites W2098392913 @default.
- W3167310167 cites W2109417276 @default.
- W3167310167 cites W2112851288 @default.
- W3167310167 cites W2114729638 @default.
- W3167310167 cites W2118090983 @default.
- W3167310167 cites W2120621087 @default.
- W3167310167 cites W2146351833 @default.
- W3167310167 cites W2147825894 @default.
- W3167310167 cites W2154899729 @default.
- W3167310167 cites W2165016676 @default.
- W3167310167 cites W2185275963 @default.
- W3167310167 cites W2220174940 @default.
- W3167310167 cites W2263587591 @default.
- W3167310167 cites W2275686970 @default.
- W3167310167 cites W2407248256 @default.
- W3167310167 cites W2523342408 @default.
- W3167310167 cites W2580713525 @default.
- W3167310167 cites W2733130888 @default.
- W3167310167 cites W2737960181 @default.
- W3167310167 cites W2776737751 @default.
- W3167310167 cites W2780093882 @default.
- W3167310167 cites W2783797611 @default.
- W3167310167 cites W2790251923 @default.
- W3167310167 cites W2793032453 @default.
- W3167310167 cites W2793344401 @default.
- W3167310167 cites W2855992536 @default.
- W3167310167 cites W2865428436 @default.
- W3167310167 cites W2883252065 @default.
- W3167310167 cites W2899937050 @default.
- W3167310167 cites W2912833196 @default.
- W3167310167 cites W2914575984 @default.
- W3167310167 cites W2964852445 @default.
- W3167310167 cites W2982700588 @default.
- W3167310167 cites W3008275218 @default.
- W3167310167 cites W3015964730 @default.
- W3167310167 cites W3039684476 @default.
- W3167310167 cites W3042766169 @default.
- W3167310167 cites W3045145397 @default.
- W3167310167 cites W3081725020 @default.
- W3167310167 cites W3093089846 @default.
- W3167310167 cites W3096805076 @default.
- W3167310167 cites W3131112041 @default.
- W3167310167 cites W3134277583 @default.
- W3167310167 cites W3144187459 @default.
- W3167310167 cites W3169629646 @default.
- W3167310167 cites W4231232103 @default.
- W3167310167 doi "https://doi.org/10.1016/j.cbpc.2021.109104" @default.
- W3167310167 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34146699" @default.
- W3167310167 hasPublicationYear "2021" @default.
- W3167310167 type Work @default.
- W3167310167 sameAs 3167310167 @default.
- W3167310167 citedByCount "8" @default.
- W3167310167 countsByYear W31673101672022 @default.
- W3167310167 countsByYear W31673101672023 @default.
- W3167310167 crossrefType "journal-article" @default.
- W3167310167 hasAuthorship W3167310167A5015012931 @default.
- W3167310167 hasAuthorship W3167310167A5015633396 @default.
- W3167310167 hasAuthorship W3167310167A5035090908 @default.
- W3167310167 hasAuthorship W3167310167A5052039809 @default.
- W3167310167 hasConcept C126322002 @default.
- W3167310167 hasConcept C134018914 @default.