Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167348567> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3167348567 endingPage "484" @default.
- W3167348567 startingPage "465" @default.
- W3167348567 abstract "Tumor cell population is a mixture of heterogeneous cell subpopulations, known as subclones. Identification of clonal status of mutations, i.e., whether a mutation occurs in all tumor cells or in a subset of tumor cells, is crucial for understanding tumor progression and developing personalized treatment strategies. We make three major contributions in this paper: (1) we summarize terminologies in the literature based on a unified mathematical representation of subclones; (2) we develop a simulation algorithm to generate hypothetical sequencing data that are akin to real data; and (3) we present an ultra-fast computational method, Mutstats, to infer clonal status of somatic mutations from sequencing data of tumors. The inference is based on a Gaussian mixture model for mutation multiplicities. To validate Mutstats, we evaluate its performance on simulated datasets as well as two breast carcinoma samples from The Cancer Genome Atlas project." @default.
- W3167348567 created "2021-06-22" @default.
- W3167348567 creator A5002847541 @default.
- W3167348567 creator A5005010286 @default.
- W3167348567 creator A5044162418 @default.
- W3167348567 creator A5080090747 @default.
- W3167348567 date "2021-01-01" @default.
- W3167348567 modified "2023-10-18" @default.
- W3167348567 title "Mutstats: An Ultra-fast Computational Method to Determine Clonal Status of Somatic Mutations" @default.
- W3167348567 cites W1809016129 @default.
- W3167348567 cites W1967304777 @default.
- W3167348567 cites W2015182193 @default.
- W3167348567 cites W2033666853 @default.
- W3167348567 cites W2062109911 @default.
- W3167348567 cites W2067256262 @default.
- W3167348567 cites W2088580309 @default.
- W3167348567 cites W2109991075 @default.
- W3167348567 cites W2111874706 @default.
- W3167348567 cites W2117608012 @default.
- W3167348567 cites W2119180969 @default.
- W3167348567 cites W2138601221 @default.
- W3167348567 cites W2139790154 @default.
- W3167348567 cites W2147841875 @default.
- W3167348567 cites W2154974159 @default.
- W3167348567 cites W2155943701 @default.
- W3167348567 cites W2157539385 @default.
- W3167348567 cites W2170490448 @default.
- W3167348567 cites W2405513305 @default.
- W3167348567 cites W2513185582 @default.
- W3167348567 cites W2519132385 @default.
- W3167348567 cites W2615097308 @default.
- W3167348567 cites W3006500278 @default.
- W3167348567 doi "https://doi.org/10.6339/21-jds1016" @default.
- W3167348567 hasPublicationYear "2021" @default.
- W3167348567 type Work @default.
- W3167348567 sameAs 3167348567 @default.
- W3167348567 citedByCount "0" @default.
- W3167348567 crossrefType "journal-article" @default.
- W3167348567 hasAuthorship W3167348567A5002847541 @default.
- W3167348567 hasAuthorship W3167348567A5005010286 @default.
- W3167348567 hasAuthorship W3167348567A5044162418 @default.
- W3167348567 hasAuthorship W3167348567A5080090747 @default.
- W3167348567 hasBestOaLocation W31673485671 @default.
- W3167348567 hasConcept C104317684 @default.
- W3167348567 hasConcept C134305767 @default.
- W3167348567 hasConcept C13514818 @default.
- W3167348567 hasConcept C141231307 @default.
- W3167348567 hasConcept C154945302 @default.
- W3167348567 hasConcept C2776214188 @default.
- W3167348567 hasConcept C2908647359 @default.
- W3167348567 hasConcept C41008148 @default.
- W3167348567 hasConcept C501734568 @default.
- W3167348567 hasConcept C54355233 @default.
- W3167348567 hasConcept C70721500 @default.
- W3167348567 hasConcept C71924100 @default.
- W3167348567 hasConcept C86803240 @default.
- W3167348567 hasConcept C99454951 @default.
- W3167348567 hasConceptScore W3167348567C104317684 @default.
- W3167348567 hasConceptScore W3167348567C134305767 @default.
- W3167348567 hasConceptScore W3167348567C13514818 @default.
- W3167348567 hasConceptScore W3167348567C141231307 @default.
- W3167348567 hasConceptScore W3167348567C154945302 @default.
- W3167348567 hasConceptScore W3167348567C2776214188 @default.
- W3167348567 hasConceptScore W3167348567C2908647359 @default.
- W3167348567 hasConceptScore W3167348567C41008148 @default.
- W3167348567 hasConceptScore W3167348567C501734568 @default.
- W3167348567 hasConceptScore W3167348567C54355233 @default.
- W3167348567 hasConceptScore W3167348567C70721500 @default.
- W3167348567 hasConceptScore W3167348567C71924100 @default.
- W3167348567 hasConceptScore W3167348567C86803240 @default.
- W3167348567 hasConceptScore W3167348567C99454951 @default.
- W3167348567 hasLocation W31673485671 @default.
- W3167348567 hasOpenAccess W3167348567 @default.
- W3167348567 hasPrimaryLocation W31673485671 @default.
- W3167348567 hasRelatedWork W1546418417 @default.
- W3167348567 hasRelatedWork W2016712296 @default.
- W3167348567 hasRelatedWork W2122019564 @default.
- W3167348567 hasRelatedWork W2152668556 @default.
- W3167348567 hasRelatedWork W2157752040 @default.
- W3167348567 hasRelatedWork W2433215378 @default.
- W3167348567 hasRelatedWork W2613868166 @default.
- W3167348567 hasRelatedWork W2762413087 @default.
- W3167348567 hasRelatedWork W2913740063 @default.
- W3167348567 hasRelatedWork W580326332 @default.
- W3167348567 isParatext "false" @default.
- W3167348567 isRetracted "false" @default.
- W3167348567 magId "3167348567" @default.
- W3167348567 workType "article" @default.