FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167404360> ?p ?o ?g. }

• W3167404360 endingPage "94" @default.
• W3167404360 startingPage "84" @default.
• W3167404360 abstract "Allograft and polyether-ether-ketone (PEEK) radiographic, biomechanical, histological properties have been extensively studied and both spacers have their advantages and shortcomings. There are no comparative randomized or double-blinded spinal fusion clinical trials reported to date.The study's primary objective was to prospectively investigate clinical and radiological outcomes in patients undergoing lumbar interbody fusions and randomized to receive either PEEK or structural bone allografts.A prospective, randomized, double-blinded clinical trial was initiated at a single center.A total of 138 patients were enrolled, randomized and 121 patients completed the study.The primary clinical outcome parameters were scored from standardized patient-reported questionnaires. The severity of lower back and leg pain was evaluated using the 11-point Visual Analog Scale (VAS). The Oswestry Disability Questionnaire was used to evaluate chronic disability and activities of daily living. Health-related quality of life and functional outcomes were assessed using Health-related Quality of Life Questionnaire (SF-36 v2). Two scores within the scoring algorithm were analyzed: Physical Component (PCS) and Mental Component Summary (MCS). The primary radiological outcomes included restoration and maintenance of vertebral body height, lumbar sagittal and segmental alignment, and fusion status.All patients were followed for 2 years ± 2 months; radiographic and clinical outcomes were assessed at 3, 6, 12 and 24 months with an additional follow-up at 3 weeks for radiographic assessment.A total of 138 patients undergoing transforaminal lumbar interbody fusions (TLIF) were randomized (1:1) to receive either cortical allograft or PEEK interbody lordotic spacers. Although no differences were detected between the allograft and PEEK patient groups at any of the follow-up time points, there was a highly significant (p<.0001) improvement in all clinical outcome measures. Overall, evidence of radiographic fusion was achieved in 118 (97.5%) patients at the 24 months follow-up. Three patients, all in the allograft group, had pseudoarthrosis and underwent revision surgeries. Postoperative improvement of sagittal alignment, anterior (ABH) or posterior body height (PBH) was initially achieved, but it was mainly lost or reduced at the final follow-up and there were no statistically significant differences between the groups. At the end of the study, improvement and maintenance of lumbar lordosis were achieved in 43.3% and 49.2% patients and segmental alignment in 38.3% and 36.1% for the allograft and PEEK patient groups, respectively. Similarly, ABH was improved and maintained in 28.3% and 36.1% patients and PBH in 28.3% and 44.3% for the allograft and PEEK groups, respectively.Although allograft-assisted surgeries may have reduced fusion rates, the study findings demonstrated that TLIF surgery with two different types of cages and in conjunction with rhBMP-2 resulted in similar radiological or clinical outcomes and a highly statistically significant improvement in all clinical outcome measures at the end of the study regardless of the randomization group." @default.
• W3167404360 created "2021-06-22" @default.
• W3167404360 creator A5001219208 @default.
• W3167404360 creator A5002037150 @default.
• W3167404360 creator A5008388695 @default.
• W3167404360 creator A5028220544 @default.
• W3167404360 creator A5065152056 @default.
• W3167404360 date "2022-01-01" @default.
• W3167404360 modified "2023-10-08" @default.
• W3167404360 title "Prospective, randomized, double-blinded clinical trial comparing PEEK and allograft spacers in patients undergoing transforaminal lumbar interbody fusion surgeries" @default.
• W3167404360 cites W1597565120 @default.
• W3167404360 cites W1625900904 @default.
• W3167404360 cites W1988903325 @default.
• W3167404360 cites W1993807248 @default.
• W3167404360 cites W2006110296 @default.
• W3167404360 cites W2007801151 @default.
• W3167404360 cites W2011756808 @default.
• W3167404360 cites W2013563232 @default.
• W3167404360 cites W2013888877 @default.
• W3167404360 cites W2051342319 @default.
• W3167404360 cites W2056574773 @default.
• W3167404360 cites W2070604339 @default.
• W3167404360 cites W2073744249 @default.
• W3167404360 cites W2100590058 @default.
• W3167404360 cites W2117594670 @default.
• W3167404360 cites W2126293572 @default.
• W3167404360 cites W2140102422 @default.
• W3167404360 cites W2159056242 @default.
• W3167404360 cites W2171957287 @default.
• W3167404360 cites W2187781852 @default.
• W3167404360 cites W2318763704 @default.
• W3167404360 cites W2332211797 @default.
• W3167404360 cites W2400097954 @default.
• W3167404360 cites W2411463077 @default.
• W3167404360 cites W2413803534 @default.
• W3167404360 cites W2605983538 @default.
• W3167404360 cites W2775961093 @default.
• W3167404360 cites W2914134698 @default.
• W3167404360 cites W2997171121 @default.
• W3167404360 cites W2999685084 @default.
• W3167404360 cites W3046303343 @default.
• W3167404360 cites W3194956376 @default.
• W3167404360 cites W4312842572 @default.
• W3167404360 cites W66035022 @default.
• W3167404360 doi "https://doi.org/10.1016/j.spinee.2021.06.005" @default.
• W3167404360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34116214" @default.
• W3167404360 hasPublicationYear "2022" @default.
• W3167404360 type Work @default.
• W3167404360 sameAs 3167404360 @default.
• W3167404360 citedByCount "5" @default.
• W3167404360 countsByYear W31674043602022 @default.
• W3167404360 countsByYear W31674043602023 @default.
• W3167404360 crossrefType "journal-article" @default.
• W3167404360 hasAuthorship W3167404360A5001219208 @default.
• W3167404360 hasAuthorship W3167404360A5002037150 @default.
• W3167404360 hasAuthorship W3167404360A5008388695 @default.
• W3167404360 hasAuthorship W3167404360A5028220544 @default.
• W3167404360 hasAuthorship W3167404360A5065152056 @default.
• W3167404360 hasConcept C126322002 @default.
• W3167404360 hasConcept C126838900 @default.
• W3167404360 hasConcept C141071460 @default.
• W3167404360 hasConcept C14184104 @default.
• W3167404360 hasConcept C142724271 @default.
• W3167404360 hasConcept C159110408 @default.
• W3167404360 hasConcept C168563851 @default.
• W3167404360 hasConcept C178910020 @default.
• W3167404360 hasConcept C1862650 @default.
• W3167404360 hasConcept C190892606 @default.
• W3167404360 hasConcept C203092338 @default.
• W3167404360 hasConcept C204787440 @default.
• W3167404360 hasConcept C2775998654 @default.
• W3167404360 hasConcept C2779951463 @default.
• W3167404360 hasConcept C2780907711 @default.
• W3167404360 hasConcept C36454342 @default.
• W3167404360 hasConcept C44575665 @default.
• W3167404360 hasConcept C535046627 @default.
• W3167404360 hasConcept C71924100 @default.
• W3167404360 hasConceptScore W3167404360C126322002 @default.
• W3167404360 hasConceptScore W3167404360C126838900 @default.
• W3167404360 hasConceptScore W3167404360C141071460 @default.
• W3167404360 hasConceptScore W3167404360C14184104 @default.
• W3167404360 hasConceptScore W3167404360C142724271 @default.
• W3167404360 hasConceptScore W3167404360C159110408 @default.
• W3167404360 hasConceptScore W3167404360C168563851 @default.
• W3167404360 hasConceptScore W3167404360C178910020 @default.
• W3167404360 hasConceptScore W3167404360C1862650 @default.
• W3167404360 hasConceptScore W3167404360C190892606 @default.
• W3167404360 hasConceptScore W3167404360C203092338 @default.
• W3167404360 hasConceptScore W3167404360C204787440 @default.
• W3167404360 hasConceptScore W3167404360C2775998654 @default.
• W3167404360 hasConceptScore W3167404360C2779951463 @default.
• W3167404360 hasConceptScore W3167404360C2780907711 @default.
• W3167404360 hasConceptScore W3167404360C36454342 @default.
• W3167404360 hasConceptScore W3167404360C44575665 @default.
• W3167404360 hasConceptScore W3167404360C535046627 @default.
• W3167404360 hasConceptScore W3167404360C71924100 @default.
• W3167404360 hasIssue "1" @default.
• W3167404360 hasLocation W31674043601 @default.

• next