Matches in SemOpenAlex for { <https://semopenalex.org/work/W3167424896> ?p ?o ?g. }
- W3167424896 abstract "The viral load of patients infected with SARS-CoV-2 varies on logarithmic scales and possibly with age. Controversial claims have been made in the literature regarding whether the viral load distribution actually depends on the age of the patients. Such a dependence would have implications for the COVID-19 spreading mechanism, the age-dependent immune system reaction, and thus for policymaking. We hereby develop a method to analyze viral-load distribution data as a function of the patients' age within a flexible, non-parametric, hierarchical, Bayesian, and causal model. This method can be applied to other contexts as well, and for this purpose, it is made freely available. The developed reconstruction method also allows testing for bias in the data. This could be due to, e.g., bias in patient-testing and data collection or systematic errors in the measurement of the viral load. We perform these tests by calculating the Bayesian evidence for each implied possible causal direction. When applying these tests to publicly available age and SARS-CoV-2 viral load data, we find a statistically significant increase in the viral load with age, but only for one of the two analyzed datasets. If we consider this dataset, and based on the current understanding of viral load's impact on patients' infectivity, we expect a non-negligible difference in the infectivity of different age groups. This difference is nonetheless too small to justify considering any age group as noninfectious." @default.
- W3167424896 created "2021-06-22" @default.
- W3167424896 creator A5003038023 @default.
- W3167424896 creator A5021624597 @default.
- W3167424896 creator A5057376602 @default.
- W3167424896 creator A5060131938 @default.
- W3167424896 creator A5074888887 @default.
- W3167424896 creator A5075381731 @default.
- W3167424896 creator A5064235944 @default.
- W3167424896 date "2021-05-27" @default.
- W3167424896 modified "2023-09-27" @default.
- W3167424896 title "Non-parametric Bayesian Causal Modeling of the SARS-CoV-2 Viral Load Distribution vs. Patient's Age" @default.
- W3167424896 cites W1196702536 @default.
- W3167424896 cites W1567012231 @default.
- W3167424896 cites W1761428853 @default.
- W3167424896 cites W1796524932 @default.
- W3167424896 cites W2045656233 @default.
- W3167424896 cites W2069429561 @default.
- W3167424896 cites W2093666167 @default.
- W3167424896 cites W2129905273 @default.
- W3167424896 cites W2795412517 @default.
- W3167424896 cites W2905325477 @default.
- W3167424896 cites W2912451899 @default.
- W3167424896 cites W2963349468 @default.
- W3167424896 cites W2996910194 @default.
- W3167424896 cites W3006561566 @default.
- W3167424896 cites W3013012439 @default.
- W3167424896 cites W3013893137 @default.
- W3167424896 cites W3016746341 @default.
- W3167424896 cites W3017257212 @default.
- W3167424896 cites W3020321870 @default.
- W3167424896 cites W3024806965 @default.
- W3167424896 cites W3025755514 @default.
- W3167424896 cites W3035125447 @default.
- W3167424896 cites W3040490521 @default.
- W3167424896 cites W3045581012 @default.
- W3167424896 cites W3046301323 @default.
- W3167424896 cites W3047719754 @default.
- W3167424896 cites W3080260201 @default.
- W3167424896 cites W3084254906 @default.
- W3167424896 cites W3092346449 @default.
- W3167424896 cites W3095153958 @default.
- W3167424896 cites W3100504522 @default.
- W3167424896 cites W3100623525 @default.
- W3167424896 cites W3111079131 @default.
- W3167424896 cites W3119715796 @default.
- W3167424896 cites W3123405708 @default.
- W3167424896 cites W3125444994 @default.
- W3167424896 cites W3126026680 @default.
- W3167424896 cites W3134773568 @default.
- W3167424896 cites W3164220019 @default.
- W3167424896 hasPublicationYear "2021" @default.
- W3167424896 type Work @default.
- W3167424896 sameAs 3167424896 @default.
- W3167424896 citedByCount "1" @default.
- W3167424896 countsByYear W31674248962021 @default.
- W3167424896 crossrefType "posted-content" @default.
- W3167424896 hasAuthorship W3167424896A5003038023 @default.
- W3167424896 hasAuthorship W3167424896A5021624597 @default.
- W3167424896 hasAuthorship W3167424896A5057376602 @default.
- W3167424896 hasAuthorship W3167424896A5060131938 @default.
- W3167424896 hasAuthorship W3167424896A5064235944 @default.
- W3167424896 hasAuthorship W3167424896A5074888887 @default.
- W3167424896 hasAuthorship W3167424896A5075381731 @default.
- W3167424896 hasConcept C105795698 @default.
- W3167424896 hasConcept C106358424 @default.
- W3167424896 hasConcept C107673813 @default.
- W3167424896 hasConcept C117251300 @default.
- W3167424896 hasConcept C126322002 @default.
- W3167424896 hasConcept C142462285 @default.
- W3167424896 hasConcept C149782125 @default.
- W3167424896 hasConcept C159047783 @default.
- W3167424896 hasConcept C2522874641 @default.
- W3167424896 hasConcept C2779134260 @default.
- W3167424896 hasConcept C3007834351 @default.
- W3167424896 hasConcept C3008058167 @default.
- W3167424896 hasConcept C33923547 @default.
- W3167424896 hasConcept C41008148 @default.
- W3167424896 hasConcept C524204448 @default.
- W3167424896 hasConcept C71924100 @default.
- W3167424896 hasConceptScore W3167424896C105795698 @default.
- W3167424896 hasConceptScore W3167424896C106358424 @default.
- W3167424896 hasConceptScore W3167424896C107673813 @default.
- W3167424896 hasConceptScore W3167424896C117251300 @default.
- W3167424896 hasConceptScore W3167424896C126322002 @default.
- W3167424896 hasConceptScore W3167424896C142462285 @default.
- W3167424896 hasConceptScore W3167424896C149782125 @default.
- W3167424896 hasConceptScore W3167424896C159047783 @default.
- W3167424896 hasConceptScore W3167424896C2522874641 @default.
- W3167424896 hasConceptScore W3167424896C2779134260 @default.
- W3167424896 hasConceptScore W3167424896C3007834351 @default.
- W3167424896 hasConceptScore W3167424896C3008058167 @default.
- W3167424896 hasConceptScore W3167424896C33923547 @default.
- W3167424896 hasConceptScore W3167424896C41008148 @default.
- W3167424896 hasConceptScore W3167424896C524204448 @default.
- W3167424896 hasConceptScore W3167424896C71924100 @default.
- W3167424896 hasLocation W31674248961 @default.
- W3167424896 hasOpenAccess W3167424896 @default.
- W3167424896 hasPrimaryLocation W31674248961 @default.
- W3167424896 hasRelatedWork W1606971570 @default.