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- W3167441346 abstract "The focus of this study is the preparation of proteinaceous human serum albumin (HSA) nanocapsules with biocompatible plant oil cores avoiding toxic cross-linker and noxious non-aqueous liquids. The sonochemical preparation of HSA capsules with different plant oils yields particles with narrow size distribution forming suspensions stable for at least 14 days and enabling long-term storage by freezing. Furthermore, wheat germ agglutinin (WGA) as a targeting molecule was successfully embedded into the proteinaceous particle shell at a molar ratio of 7:1 (HSA/WGA). As urothelial cell binding studies revealed up to 55% higher cell binding potential of WGA-grafted particles than those without a targeter, targeted protein nanocapsules represent the first step towards new and innovative formulations." @default.
- W3167441346 created "2021-06-22" @default.
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- W3167441346 date "2021-08-01" @default.
- W3167441346 modified "2023-09-26" @default.
- W3167441346 title "Characterization of sonochemically prepared human serum albumin nanocapsules using different plant oils as core component for targeted drug delivery" @default.
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- W3167441346 doi "https://doi.org/10.1016/j.ultsonch.2021.105617" @default.
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