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• W3167698965 abstract "Human dexterous motor control improves from childhood to adulthood, but little is known about the changes in cortico-cortical communication that support such ontogenetic refinement of motor skills. To investigate age-related differences in connectivity between cortical regions involved in dexterous control, we analyzed electroencephalographic data from 88 individuals (range 8-30 years) performing a visually guided precision grip task using dynamic causal modelling and parametric empirical Bayes. Our results demonstrate that bidirectional coupling in a canonical ‘grasping network’ is associated with precision grip performance across age groups. We further demonstrate greater backward coupling from higher-order to lower-order sensorimotor regions from late adolescence in addition to differential associations between connectivity strength in a premotor-prefrontal network and motor performance for different age groups. We interpret these findings as reflecting greater use of top-down and executive control processes with development. These results expand our understanding of the cortical mechanisms that support dexterous abilities through development." @default.
• W3167698965 created "2021-06-22" @default.
• W3167698965 creator A5002965207 @default.
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• W3167698965 date "2021-06-14" @default.
• W3167698965 modified "2023-09-26" @default.
• W3167698965 title "Cortical signatures of precision grip force control in children, adolescents, and adults" @default.
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• W3167698965 doi "https://doi.org/10.7554/elife.61018" @default.
• W3167698965 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8216716" @default.
• W3167698965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34121656" @default.
• W3167698965 hasPublicationYear "2021" @default.
• W3167698965 type Work @default.
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