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• W3168027355 abstract "In this work, an attempt was made to develop a powerful method for the determination of cefixime, as a widely used cephalosporin antibiotic. The method was based on the facile extraction and preconcentration of cefixime using Zn metal–organic framework doped magnetic graphene oxide composite ([email protected]), followed by its determination using high-performance liquid chromatography (HPLC). The high surface area, great stability, and distinct features of the new adsorbent made it ideal for very efficient interactions with analyte molecules. [email protected] was able to effectively extract cefixime from the complex matrix of real samples. Furthermore, the application of the magnetic-solid phase extraction (MSPE) process provided a low-cost and simple extraction process with a reduced extraction time. The combination of a high-performance extraction with a potent HPLC system resulted in a highly sensitive and selective analytical detection method. The method was able to detect cefixime in a linear range of 0.5–130 ng mL−1, with a detection limit of 0.11 ng mL−1, no important interfering effect was caused by other examined drugs. It was examined for the analysis of cefixime content of pharmaceutical and biological samples and acceptable recovery values were obtained." @default.
• W3168027355 created "2021-06-22" @default.
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• W3168027355 date "2021-10-01" @default.
• W3168027355 modified "2023-09-30" @default.
• W3168027355 title "Synthesis of Zn metal–organic framework doped magnetic graphene oxide for preconcentration and extraction of cefixime followed by its measurement using HPLC" @default.
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• W3168027355 doi "https://doi.org/10.1016/j.microc.2021.106537" @default.
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