Matches in SemOpenAlex for { <https://semopenalex.org/work/W3168522026> ?p ?o ?g. }
- W3168522026 abstract "Background Observational studies suggest that hormonal contraceptive use may increase depressive symptoms in women, but it is unclear whether the effect is causal. Aims To quantitatively examine the evidence from randomised clinical trials for the link between hormonal contraceptive use and depressive symptoms. Method We performed a systematic review and network meta-analysis of randomised clinical trials comparing women randomised to any form of a hormonal contraceptive with women randomised to any other form of a (non-)hormonal contraceptive or placebo. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Web of Science, PsycINFO, EMCare and EMBASE, from inception to 1 May 2020. Certainty of the evidence was assessed with the Grading of Recommendations Assessment, Development and Evaluation approach. A random-effect Bayesian network meta-analysis was conducted, with change in depressive symptoms between baseline and three cycles as outcome. Results This review identified 3492 records, of which 14 trials were eligible and 12 could be included in the network meta-analysis. These trials included 5833 participants (mean age per study range: 16.8–32.4 years) and compared 10 different interventions. Compared with placebo, hormonal contraceptive use did not cause worsening of depressive symptoms (standardised mean difference: median, −0.04; range, −0.17 [95% credible interval −0.46 to 0.13] to 0.13 [95% credible interval −0.28 to 0.56]). Conclusions This study suggests that hormonal contraceptive use does not lead to an increase in depressive symptoms in adult women. Future studies should include first-time users, to confirm the results in young women." @default.
- W3168522026 created "2021-06-22" @default.
- W3168522026 creator A5016729649 @default.
- W3168522026 creator A5026480246 @default.
- W3168522026 creator A5029095137 @default.
- W3168522026 creator A5030799981 @default.
- W3168522026 creator A5043197939 @default.
- W3168522026 creator A5048041048 @default.
- W3168522026 creator A5067854504 @default.
- W3168522026 date "2021-06-08" @default.
- W3168522026 modified "2023-10-03" @default.
- W3168522026 title "Hormonal contraceptive use and depressive symptoms: systematic review and network meta-analysis of randomised trials" @default.
- W3168522026 cites W155562407 @default.
- W3168522026 cites W180781522 @default.
- W3168522026 cites W1941651633 @default.
- W3168522026 cites W1971959108 @default.
- W3168522026 cites W1977937012 @default.
- W3168522026 cites W1993527198 @default.
- W3168522026 cites W2003892706 @default.
- W3168522026 cites W2012712382 @default.
- W3168522026 cites W2031648422 @default.
- W3168522026 cites W2044884461 @default.
- W3168522026 cites W2073679198 @default.
- W3168522026 cites W2074895699 @default.
- W3168522026 cites W2076029586 @default.
- W3168522026 cites W2084001086 @default.
- W3168522026 cites W2084209580 @default.
- W3168522026 cites W2119529166 @default.
- W3168522026 cites W2121299515 @default.
- W3168522026 cites W2130048482 @default.
- W3168522026 cites W2144269887 @default.
- W3168522026 cites W2147730609 @default.
- W3168522026 cites W2163731846 @default.
- W3168522026 cites W2166505304 @default.
- W3168522026 cites W2418658227 @default.
- W3168522026 cites W2514601392 @default.
- W3168522026 cites W2558994652 @default.
- W3168522026 cites W2607280494 @default.
- W3168522026 cites W2737812429 @default.
- W3168522026 cites W2766211624 @default.
- W3168522026 cites W2792068262 @default.
- W3168522026 cites W2794152168 @default.
- W3168522026 cites W2808445276 @default.
- W3168522026 cites W2970684805 @default.
- W3168522026 cites W2978659044 @default.
- W3168522026 cites W3015163167 @default.
- W3168522026 cites W4213280137 @default.
- W3168522026 cites W4255497623 @default.
- W3168522026 doi "https://doi.org/10.1192/bjo.2021.64" @default.
- W3168522026 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8220855" @default.
- W3168522026 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34099098" @default.
- W3168522026 hasPublicationYear "2021" @default.
- W3168522026 type Work @default.
- W3168522026 sameAs 3168522026 @default.
- W3168522026 citedByCount "6" @default.
- W3168522026 countsByYear W31685220262022 @default.
- W3168522026 countsByYear W31685220262023 @default.
- W3168522026 crossrefType "journal-article" @default.
- W3168522026 hasAuthorship W3168522026A5016729649 @default.
- W3168522026 hasAuthorship W3168522026A5026480246 @default.
- W3168522026 hasAuthorship W3168522026A5029095137 @default.
- W3168522026 hasAuthorship W3168522026A5030799981 @default.
- W3168522026 hasAuthorship W3168522026A5043197939 @default.
- W3168522026 hasAuthorship W3168522026A5048041048 @default.
- W3168522026 hasAuthorship W3168522026A5067854504 @default.
- W3168522026 hasBestOaLocation W31685220261 @default.
- W3168522026 hasConcept C126322002 @default.
- W3168522026 hasConcept C142724271 @default.
- W3168522026 hasConcept C168563851 @default.
- W3168522026 hasConcept C17744445 @default.
- W3168522026 hasConcept C199539241 @default.
- W3168522026 hasConcept C204787440 @default.
- W3168522026 hasConcept C23131810 @default.
- W3168522026 hasConcept C27081682 @default.
- W3168522026 hasConcept C2779473830 @default.
- W3168522026 hasConcept C2779549880 @default.
- W3168522026 hasConcept C535046627 @default.
- W3168522026 hasConcept C71924100 @default.
- W3168522026 hasConcept C95190672 @default.
- W3168522026 hasConceptScore W3168522026C126322002 @default.
- W3168522026 hasConceptScore W3168522026C142724271 @default.
- W3168522026 hasConceptScore W3168522026C168563851 @default.
- W3168522026 hasConceptScore W3168522026C17744445 @default.
- W3168522026 hasConceptScore W3168522026C199539241 @default.
- W3168522026 hasConceptScore W3168522026C204787440 @default.
- W3168522026 hasConceptScore W3168522026C23131810 @default.
- W3168522026 hasConceptScore W3168522026C27081682 @default.
- W3168522026 hasConceptScore W3168522026C2779473830 @default.
- W3168522026 hasConceptScore W3168522026C2779549880 @default.
- W3168522026 hasConceptScore W3168522026C535046627 @default.
- W3168522026 hasConceptScore W3168522026C71924100 @default.
- W3168522026 hasConceptScore W3168522026C95190672 @default.
- W3168522026 hasIssue "4" @default.
- W3168522026 hasLocation W31685220261 @default.
- W3168522026 hasLocation W31685220262 @default.
- W3168522026 hasLocation W31685220263 @default.
- W3168522026 hasLocation W31685220264 @default.
- W3168522026 hasLocation W31685220265 @default.
- W3168522026 hasOpenAccess W3168522026 @default.
- W3168522026 hasPrimaryLocation W31685220261 @default.