FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3168656721> ?p ?o ?g. }

• W3168656721 endingPage "1994" @default.
• W3168656721 startingPage "1979" @default.
• W3168656721 abstract "Long non-coding RNAs (lncRNAs) play key roles in various human cancers. We aimed to determine the key lncRNAs mediating colorectal cancer (CRC) progression. We identified some lncRNAs aberrantly expressed in CRC tissues by using lncRNA microarrays and demonstrated that SH3PXD2A-AS1 was one of the most highly overexpressed lncRNAs in CRC. We further aimed to explore the roles and possible molecular mechanisms of SH3PXD2A-AS1 in CRC. RNA ISH revealed that SH3PXD2A-AS1 was overexpressed in CRC compared with adjacent normal colon tissues and indicated poor prognosis in CRC. Functional analyses showed that SH3PXD2A-AS1 enhanced cell proliferation, angiogenesis, and metastasis. Mechanistically, SH3PXD2A-AS1 can directly interact with p53 protein and regulate p53-mediated gene transcription in CRC. We provided mechanistic insights into the regulation of SH3PXD2A-AS1 on p53-mediated gene transcription and suggested its potential as a new prognostic biomarker and target for the clinical management of CRC." @default.
• W3168656721 created "2021-06-22" @default.
• W3168656721 creator A5002701776 @default.
• W3168656721 creator A5009763275 @default.
• W3168656721 creator A5027899503 @default.
• W3168656721 creator A5028924750 @default.
• W3168656721 creator A5035555749 @default.
• W3168656721 creator A5041008078 @default.
• W3168656721 creator A5042022280 @default.
• W3168656721 creator A5062275094 @default.
• W3168656721 creator A5067016617 @default.
• W3168656721 creator A5072548035 @default.
• W3168656721 creator A5091364490 @default.
• W3168656721 date "2021-01-01" @default.
• W3168656721 modified "2023-10-13" @default.
• W3168656721 title "Long noncoding RNA SH3PXD2A-AS1 promotes colorectal cancer progression by regulating p53-mediated gene transcription" @default.
• W3168656721 cites W1893561328 @default.
• W3168656721 cites W1944995278 @default.
• W3168656721 cites W1964719993 @default.
• W3168656721 cites W1967659443 @default.
• W3168656721 cites W1967708173 @default.
• W3168656721 cites W1977572305 @default.
• W3168656721 cites W1995394695 @default.
• W3168656721 cites W2003870059 @default.
• W3168656721 cites W2015186671 @default.
• W3168656721 cites W2032995169 @default.
• W3168656721 cites W2051131006 @default.
• W3168656721 cites W2067517099 @default.
• W3168656721 cites W2071271349 @default.
• W3168656721 cites W2074023224 @default.
• W3168656721 cites W2081777966 @default.
• W3168656721 cites W2083033504 @default.
• W3168656721 cites W2105829583 @default.
• W3168656721 cites W2126504590 @default.
• W3168656721 cites W2130410032 @default.
• W3168656721 cites W2148532468 @default.
• W3168656721 cites W2153268494 @default.
• W3168656721 cites W2155063664 @default.
• W3168656721 cites W2168347591 @default.
• W3168656721 cites W2235841654 @default.
• W3168656721 cites W2272984102 @default.
• W3168656721 cites W2464944724 @default.
• W3168656721 cites W2525843044 @default.
• W3168656721 cites W2606864213 @default.
• W3168656721 cites W2607129810 @default.
• W3168656721 cites W2750180661 @default.
• W3168656721 cites W2758252083 @default.
• W3168656721 cites W2761249484 @default.
• W3168656721 cites W2768096340 @default.
• W3168656721 cites W2769004457 @default.
• W3168656721 cites W2792883124 @default.
• W3168656721 cites W2799377021 @default.
• W3168656721 cites W2799785541 @default.
• W3168656721 cites W2802552316 @default.
• W3168656721 cites W2803519014 @default.
• W3168656721 cites W2809263068 @default.
• W3168656721 cites W2871099016 @default.
• W3168656721 cites W2885912277 @default.
• W3168656721 cites W2886875659 @default.
• W3168656721 cites W2902210515 @default.
• W3168656721 cites W2947606238 @default.
• W3168656721 cites W2958448895 @default.
• W3168656721 cites W2963504068 @default.
• W3168656721 cites W2967430965 @default.
• W3168656721 cites W2968816674 @default.
• W3168656721 cites W3110629027 @default.
• W3168656721 doi "https://doi.org/10.7150/ijbs.58422" @default.
• W3168656721 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8193262" @default.
• W3168656721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34131400" @default.
• W3168656721 hasPublicationYear "2021" @default.
• W3168656721 type Work @default.
• W3168656721 sameAs 3168656721 @default.
• W3168656721 citedByCount "6" @default.
• W3168656721 countsByYear W31686567212022 @default.
• W3168656721 countsByYear W31686567212023 @default.
• W3168656721 crossrefType "journal-article" @default.
• W3168656721 hasAuthorship W3168656721A5002701776 @default.
• W3168656721 hasAuthorship W3168656721A5009763275 @default.
• W3168656721 hasAuthorship W3168656721A5027899503 @default.
• W3168656721 hasAuthorship W3168656721A5028924750 @default.
• W3168656721 hasAuthorship W3168656721A5035555749 @default.
• W3168656721 hasAuthorship W3168656721A5041008078 @default.
• W3168656721 hasAuthorship W3168656721A5042022280 @default.
• W3168656721 hasAuthorship W3168656721A5062275094 @default.
• W3168656721 hasAuthorship W3168656721A5067016617 @default.
• W3168656721 hasAuthorship W3168656721A5072548035 @default.
• W3168656721 hasAuthorship W3168656721A5091364490 @default.
• W3168656721 hasBestOaLocation W31686567211 @default.
• W3168656721 hasConcept C104317684 @default.
• W3168656721 hasConcept C121608353 @default.
• W3168656721 hasConcept C138885662 @default.
• W3168656721 hasConcept C150194340 @default.
• W3168656721 hasConcept C179926584 @default.
• W3168656721 hasConcept C2779013556 @default.
• W3168656721 hasConcept C2780394083 @default.
• W3168656721 hasConcept C2781197716 @default.
• W3168656721 hasConcept C41895202 @default.
• W3168656721 hasConcept C502942594 @default.

• next