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- W3168889717 abstract "Osteoporosis, as a skeletal disorder characterized by gradually reduced bone mineral density, is a severe threat to millions of postmenopausal women. MicroRNAs (miRNAs) are important post-transcriptional factors and play an important role in bone degeneration such as osteoporosis and other bone-related diseases. Here we showed that the expression of miR-29b in bone tissue and bone marrow stromal cells (BMSCs) of Ovx mice is descend and overexpression of miR-29b could partially rescued osteogenic differentiation and bone formation ability of Ovx-BMSCs in vitro and in vivo, respectively. Our studies indicated that miR-29b plays an important role in regulating BMSCs osteogenic differentiation and could contribute to osteoporosis therapy." @default.
- W3168889717 created "2021-06-22" @default.
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- W3168889717 date "2021-04-08" @default.
- W3168889717 modified "2023-09-30" @default.
- W3168889717 title "Overexpression of miR-29b Partially Rescued the Osteogenic Differentiation and Osteogenesis Ability of Ovx-BMSCs" @default.
- W3168889717 doi "https://doi.org/10.34297/ajbsr.2021.12.001761" @default.
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