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- W3168920815 abstract "Objective: The objective of this work is to synthesize new molecules with biological characteristics against some infectious germs.
 Methods: The method of synthesis is based on the exploitation of the reactivity of the position-1 of the benzimidazole. It consisted of reacting the bis-benzimidazole 5 with the 1,2-dicloroethane in a solution of NaOH 2N (6,4%). The compound 6 is refluxed with ethanol with the different thioaryls to lead to compounds 7.
 Results: Thus, a series of molecules derived from bis-benzimidazoles were synthesized including N-alkylated 6 and 7a-d. The characterization of these newly synthesized compounds was performed by NMR (1H and 13C) and mass spectroscopy methods.
 Conclusion: The purified and characterized compounds 6 and 7a-d allow the development of a new chemical class of anti-infectives." @default.
- W3168920815 created "2021-06-22" @default.
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- W3168920815 date "2021-06-01" @default.
- W3168920815 modified "2023-10-17" @default.
- W3168920815 title "SYNTHESIS OF BIS-BENZIMIDAZOLES N-ALKYL ANTI-INFECTIOUS DERIVATES" @default.
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- W3168920815 doi "https://doi.org/10.22159/ijpps.2021v13i6.40310" @default.
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