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- W3169219005 endingPage "65" @default.
- W3169219005 startingPage "49" @default.
- W3169219005 abstract "Innumerable microbiota in the gut are known to affect human behavior. The immune and endocrine systems are involved in the bidirectional communication between the gut and brain, which is regulated by bacteria via metabolism of microbiome-derived neurocompounds and tryptophan. In a commensal relationship, microbiota have a certain effect on the development of nerves; however, in dysbiosis, they can cause neuropsychiatric illnesses. Such disturbances have been identified through behavioral and biomarker studies of sterile samples in animals such as zebrafish and mice. Recent clinical studies have shown that the gut microbiome affects human behavior through multiple pathways. Dysbiosis of the gut microbiome is associated with neuropsychiatric disorders and the use of antibiotics, administration of probiotics, and fecal microbial transplantation could be beneficial in patients with mental disorders. In this chapter, we summarize the communication pathways of the brain–gut axis and examine the evidence of how the gut microbiome affects this axis in human neuropsychiatric disorders." @default.
- W3169219005 created "2021-06-22" @default.
- W3169219005 creator A5018353241 @default.
- W3169219005 creator A5086727096 @default.
- W3169219005 date "2021-01-01" @default.
- W3169219005 modified "2023-09-27" @default.
- W3169219005 title "The interactions between gut and brain in psychiatric and neurological disorders" @default.
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