Matches in SemOpenAlex for { <https://semopenalex.org/work/W3169345916> ?p ?o ?g. }
- W3169345916 endingPage "e07308" @default.
- W3169345916 startingPage "e07308" @default.
- W3169345916 abstract "<h2>Abstract</h2> Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system (ENS) derived from neural crest cells (NCCs), which affects their migration, proliferation, differentiation, or preservation in the digestive tract, resulting in aganglionosis in the distal intestine. The regulation of both NCCs and the surrounding environment involves various genes, signaling pathways, transcription factors, and morphogens. Therefore, changes in gene expression during the development of the ENS may contribute to the pathogenesis of HSCR. This review discusses several mechanisms involved in the development of ENS, confirming that deviant genetic and epigenetic patterns, such as DNA methylation, histone modification, and microRNA (miRNA) regulation, can contribute to the development of neurocristopathy. Specifically, the epigenetic regulation of miRNA expression and its relationship to cellular interactions and gene activation through various major pathways in Hirschsprung's disease will be discussed." @default.
- W3169345916 created "2021-06-22" @default.
- W3169345916 creator A5000512240 @default.
- W3169345916 creator A5013341998 @default.
- W3169345916 creator A5032179703 @default.
- W3169345916 creator A5033071708 @default.
- W3169345916 creator A5038352479 @default.
- W3169345916 date "2021-06-01" @default.
- W3169345916 modified "2023-10-10" @default.
- W3169345916 title "Literature review: enteric nervous system development, genetic and epigenetic regulation in the etiology of Hirschsprung's disease" @default.
- W3169345916 cites W1766156201 @default.
- W3169345916 cites W1919489720 @default.
- W3169345916 cites W1949798014 @default.
- W3169345916 cites W1951867641 @default.
- W3169345916 cites W1966432641 @default.
- W3169345916 cites W1967461831 @default.
- W3169345916 cites W1967571151 @default.
- W3169345916 cites W1967803008 @default.
- W3169345916 cites W1969036097 @default.
- W3169345916 cites W1970225272 @default.
- W3169345916 cites W1971033887 @default.
- W3169345916 cites W1972493712 @default.
- W3169345916 cites W1974450480 @default.
- W3169345916 cites W1974973864 @default.
- W3169345916 cites W1976989940 @default.
- W3169345916 cites W1977112586 @default.
- W3169345916 cites W1979816705 @default.
- W3169345916 cites W1979856980 @default.
- W3169345916 cites W1980269624 @default.
- W3169345916 cites W1983441272 @default.
- W3169345916 cites W1984818226 @default.
- W3169345916 cites W1984838392 @default.
- W3169345916 cites W1985065420 @default.
- W3169345916 cites W1986631342 @default.
- W3169345916 cites W1988723616 @default.
- W3169345916 cites W1989174024 @default.
- W3169345916 cites W1990339051 @default.
- W3169345916 cites W1991750645 @default.
- W3169345916 cites W1994436997 @default.
- W3169345916 cites W1994645662 @default.
- W3169345916 cites W1995073275 @default.
- W3169345916 cites W1995653718 @default.
- W3169345916 cites W1995888456 @default.
- W3169345916 cites W1998527587 @default.
- W3169345916 cites W1999259704 @default.
- W3169345916 cites W2001247463 @default.
- W3169345916 cites W2004172747 @default.
- W3169345916 cites W2008118174 @default.
- W3169345916 cites W2008748143 @default.
- W3169345916 cites W2011813261 @default.
- W3169345916 cites W2013357559 @default.
- W3169345916 cites W2014946489 @default.
- W3169345916 cites W2020745684 @default.
- W3169345916 cites W2023285758 @default.
- W3169345916 cites W2025149315 @default.
- W3169345916 cites W2028093783 @default.
- W3169345916 cites W2029612353 @default.
- W3169345916 cites W2030996806 @default.
- W3169345916 cites W2035681587 @default.
- W3169345916 cites W2039790417 @default.
- W3169345916 cites W2041561035 @default.
- W3169345916 cites W2045756232 @default.
- W3169345916 cites W2046739515 @default.
- W3169345916 cites W2047222236 @default.
- W3169345916 cites W2049347850 @default.
- W3169345916 cites W2049910739 @default.
- W3169345916 cites W2051313028 @default.
- W3169345916 cites W2052512069 @default.
- W3169345916 cites W2052639401 @default.
- W3169345916 cites W2054593736 @default.
- W3169345916 cites W2054807249 @default.
- W3169345916 cites W2055210467 @default.
- W3169345916 cites W2055718694 @default.
- W3169345916 cites W2056594982 @default.
- W3169345916 cites W2057306230 @default.
- W3169345916 cites W2059177632 @default.
- W3169345916 cites W2064464220 @default.
- W3169345916 cites W2065657493 @default.
- W3169345916 cites W2066784652 @default.
- W3169345916 cites W2067003013 @default.
- W3169345916 cites W2068634777 @default.
- W3169345916 cites W2068732134 @default.
- W3169345916 cites W2070826332 @default.
- W3169345916 cites W2078885578 @default.
- W3169345916 cites W2081316343 @default.
- W3169345916 cites W2083101784 @default.
- W3169345916 cites W2083248512 @default.
- W3169345916 cites W2086538740 @default.
- W3169345916 cites W2087447340 @default.
- W3169345916 cites W2089348287 @default.
- W3169345916 cites W2090159403 @default.
- W3169345916 cites W2094613173 @default.
- W3169345916 cites W2095591360 @default.
- W3169345916 cites W2096194550 @default.
- W3169345916 cites W2098528059 @default.
- W3169345916 cites W2104560040 @default.
- W3169345916 cites W2105946812 @default.
- W3169345916 cites W2106482095 @default.