FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3169409246> ?p ?o ?g. }

• W3169409246 endingPage "536" @default.
• W3169409246 startingPage "536" @default.
• W3169409246 abstract "The main objective of this work is to evaluate the effect of a diet rich in antioxidants based on mesquite seed on the atherogenic index of the dislipidemia-prone C57BL/6J mouse. Mesquite seed based diet with 18% of protein was prepared using flour of mesquite seed, corn and micronutrient mix. Additionally, a diet based on casein with 18% of protein was preparing using casein, corn flour, wheat bran and micronutrient mix. Both diets were processed by extrusion. Extruded diets were analyzed for proximal composition, flavonoids content (HPLC) and radical scavenging capacity. For mice biological assay development, a bioethically approved protocol was used. Four-week-old male C57BL/6J mice were used. One group of mice (n = 6) was fed a diet based on mesquite seed and a second group (n = 6) was fed a diet based on casein from week 4 to week 18 of life. Mice were maintained with free access to food and water. At the end of the experimental period, blood samples were taken for the determination of total cholesterol (TC), and high-density lipoprotein cholesterol (HDL-c) using dry-chemistry enzymatic slide technology. The atherogenic index (AI) was calculated using the formula: AI = TC (mg/dL)/HDL-c (mg/dL). The caloric content of the diet based on mesquite seed and the diet based on casein were 373.1 and 365.1 kcal/100g, respectively. The energy intake of mice treated with mesquite and casein diet were 13.43 and 13.51 kcal/day, respectively. The phenolic compounds intake of mice treated with mesquite and casein diet were 8.3 and 1.9 mg/day, respectively. The atherogenic index in mice treated with a diet based on mesquite seed was 2.25 and for the mice treated with a diet based on casein was 3.31. After 14 weeks of a diet based on mesquite seed C57BL/6J mice presented significantly lower levels of total cholesterol and atherogenic index than mice treated with a diet based on casein. Diet based on mesquite seed lead to higher intakes of phenolic compounds and antioxidants than a diet based on casein. The C57BL/6J mouse is a nicotinamide nucleotide transhydrogenase deficient model, which induces oxidative stress and insulin resistance. This condition increases the susceptibility to develops dyslipidemia, diabetes and obesity. A diet based on mesquite seed prevents dyslipidemia development in C57BL/6J. No funding." @default.
• W3169409246 created "2021-06-22" @default.
• W3169409246 creator A5034696931 @default.
• W3169409246 creator A5087645696 @default.
• W3169409246 date "2021-06-01" @default.
• W3169409246 modified "2023-09-30" @default.
• W3169409246 title "A Diet Based on Mesquite Seed Improves Atherogenic Index in Mouse Model" @default.
• W3169409246 doi "https://doi.org/10.1093/cdn/nzab042_003" @default.
• W3169409246 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8181952" @default.
• W3169409246 hasPublicationYear "2021" @default.
• W3169409246 type Work @default.
• W3169409246 sameAs 3169409246 @default.
• W3169409246 citedByCount "0" @default.
• W3169409246 crossrefType "journal-article" @default.
• W3169409246 hasAuthorship W3169409246A5034696931 @default.
• W3169409246 hasAuthorship W3169409246A5087645696 @default.
• W3169409246 hasBestOaLocation W31694092461 @default.
• W3169409246 hasConcept C138885662 @default.
• W3169409246 hasConcept C140793950 @default.
• W3169409246 hasConcept C14522933 @default.
• W3169409246 hasConcept C178790620 @default.
• W3169409246 hasConcept C185592680 @default.
• W3169409246 hasConcept C206139338 @default.
• W3169409246 hasConcept C2776142715 @default.
• W3169409246 hasConcept C2776873940 @default.
• W3169409246 hasConcept C2778163477 @default.
• W3169409246 hasConcept C31903555 @default.
• W3169409246 hasConcept C40231798 @default.
• W3169409246 hasConcept C41895202 @default.
• W3169409246 hasConcept C55493867 @default.
• W3169409246 hasConcept C86803240 @default.
• W3169409246 hasConceptScore W3169409246C138885662 @default.
• W3169409246 hasConceptScore W3169409246C140793950 @default.
• W3169409246 hasConceptScore W3169409246C14522933 @default.
• W3169409246 hasConceptScore W3169409246C178790620 @default.
• W3169409246 hasConceptScore W3169409246C185592680 @default.
• W3169409246 hasConceptScore W3169409246C206139338 @default.
• W3169409246 hasConceptScore W3169409246C2776142715 @default.
• W3169409246 hasConceptScore W3169409246C2776873940 @default.
• W3169409246 hasConceptScore W3169409246C2778163477 @default.
• W3169409246 hasConceptScore W3169409246C31903555 @default.
• W3169409246 hasConceptScore W3169409246C40231798 @default.
• W3169409246 hasConceptScore W3169409246C41895202 @default.
• W3169409246 hasConceptScore W3169409246C55493867 @default.
• W3169409246 hasConceptScore W3169409246C86803240 @default.
• W3169409246 hasLocation W31694092461 @default.
• W3169409246 hasLocation W31694092462 @default.
• W3169409246 hasOpenAccess W3169409246 @default.
• W3169409246 hasPrimaryLocation W31694092461 @default.
• W3169409246 hasRelatedWork W1502671072 @default.
• W3169409246 hasRelatedWork W1989550583 @default.
• W3169409246 hasRelatedWork W1994328769 @default.
• W3169409246 hasRelatedWork W2151343980 @default.
• W3169409246 hasRelatedWork W2473541584 @default.
• W3169409246 hasRelatedWork W278595897 @default.
• W3169409246 hasRelatedWork W3026910243 @default.
• W3169409246 hasRelatedWork W3211528688 @default.
• W3169409246 hasRelatedWork W4282837692 @default.
• W3169409246 hasRelatedWork W775372238 @default.
• W3169409246 hasVolume "5" @default.
• W3169409246 isParatext "false" @default.
• W3169409246 isRetracted "false" @default.
• W3169409246 magId "3169409246" @default.
• W3169409246 workType "article" @default.