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- W3170228749 abstract "Rat electrophysiological measurements are widely used in experimental protocols to study heart diseases, drug assessment, and their interaction. However, commercially employed rat ECG recording systems demand a high cost for implantation due to the increased signal conditioning complexity and experimental arrangements compared to the ECG from a human subject. These issues preclude its greater use for experimental research in emerging countries. In this perspective, we designed and implemented a low-cost, simplified system for recording the cardiac electric activity in rats, meeting the minimum specifications for suitable data processing. The hardware developed in the system consisted of four blocks, including conditioning, conversion, transmission, and system power supply; the acquired signals are stored and processed on a personal computer. Our system demonstrated capacity for recording ECG signals successfully with low-noise and minimum requirements. Also, data analysis showed that with simple filtering was possible to identify the R peak, allowing the further analysis of ECG rhythmicity and morphology and calculation of heart rate variability indexes. Therefore, we concluded that this low-cost system proved to be adequate for ECG recording in rats. Nonetheless, we encouraged further work to better assessment in the different experimental protocols and other rodents.KeywordsElectrophysiologyECG recordingLow noise amplifierRat" @default.
- W3170228749 created "2021-06-22" @default.
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- W3170228749 date "2021-01-01" @default.
- W3170228749 modified "2023-10-17" @default.
- W3170228749 title "Design and Implementation of an ECG Recording System for in Vivo Experimentation in Rats" @default.
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- W3170228749 doi "https://doi.org/10.1007/978-3-030-75680-2_37" @default.
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