FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3170293810> ?p ?o ?g. }

• W3170293810 endingPage "107821" @default.
• W3170293810 startingPage "107821" @default.
• W3170293810 abstract "This study aimed to discuss the expression of angiogenesis-related proteins in bone marrow mesenchymal stem cells (BMSCs) induced by osteoprotegerin (OGP) during osteogenic differentiation in rats, and to analyze the effect of fracture healing inflammatory factor TNF-ɑ on the osteogenic differentiation of BMSCs of rats. BMSCs isolated and cultured from the third generation rats were taken as the research object. According to the addition amount of OGP, BMSCs were divided into control group, OGP (10-7 mol/L) group, OGP (10-8 mol/L) group, and OGP (10-9 mol/L) group. The cell growth and morphological characteristics of each group were observed by inverted phase contrast microscope, the cell proliferation rate was measured by MTT method, angiogenesis-related markers (platelet growth factor (VEGF), cingulate protein 5 (Fbln5), and angiogenin-like protein 4 (Angptl4)) were quantitatively detected by Western blot, and the effect of TNF-ɑ on osteogenic differentiation was detected by CCK. Compared with the control group, MTT results showed that the value-added rate of cells in the OGP (10-8 mol/L) group reached the maximum at 9 days (P < 0.05). The ALP activity in osteoblasts in the OGP (10-8 mol/L) group reached the maximum at 9 days (P < 0.01). The OGP (10-8 mol/L) group had the highest expression of vascular regeneration proteins (VEGF, Fbln5, and Angptl4) (P < 0.05). CCK analysis showed that the TNF-ɑ (1.0 ng/mL) group showed a significant increase in absorbance compared with the control group on 6 days (P < 0.05), and the OD value of the TNF-ɑ (10 ng/mL) group decreased at all time points (P < 0.05). Overall, 10-8 mol/L OGP can induce the proliferation and osteogenic differentiation of MSCs, and promote the expression of angiogenesis-related proteins (VEGF, Fbln5, and Angptl4) during osteogenic differentiation. Besides, 1.0 ng/mL of TNF-ɑ can also promote osteogenesis differentiation of BMSCs in the short term." @default.
• W3170293810 created "2021-06-22" @default.
• W3170293810 creator A5046597133 @default.
• W3170293810 creator A5056168495 @default.
• W3170293810 date "2021-09-01" @default.
• W3170293810 modified "2023-09-25" @default.
• W3170293810 title "Expression of angiogenesis-related proteins in bone marrow mesenchymal stem cells induced by osteoprotegerin during osteogenic differentiation in rats" @default.
• W3170293810 cites W1561181013 @default.
• W3170293810 cites W1607471435 @default.
• W3170293810 cites W1970709580 @default.
• W3170293810 cites W2004565753 @default.
• W3170293810 cites W2007564570 @default.
• W3170293810 cites W2012988891 @default.
• W3170293810 cites W2022558733 @default.
• W3170293810 cites W2027745827 @default.
• W3170293810 cites W2031188779 @default.
• W3170293810 cites W2038399651 @default.
• W3170293810 cites W2044596336 @default.
• W3170293810 cites W2093727964 @default.
• W3170293810 cites W2145121923 @default.
• W3170293810 cites W2145291679 @default.
• W3170293810 cites W2160222000 @default.
• W3170293810 cites W2225056950 @default.
• W3170293810 cites W2417433458 @default.
• W3170293810 cites W2475874939 @default.
• W3170293810 cites W2525605182 @default.
• W3170293810 cites W2559380558 @default.
• W3170293810 cites W2564655258 @default.
• W3170293810 cites W2582210304 @default.
• W3170293810 cites W2583063590 @default.
• W3170293810 cites W2625972055 @default.
• W3170293810 cites W2770882579 @default.
• W3170293810 cites W2891628252 @default.
• W3170293810 cites W2891991747 @default.
• W3170293810 cites W2910235056 @default.
• W3170293810 cites W2911460021 @default.
• W3170293810 cites W2913564338 @default.
• W3170293810 cites W2920624232 @default.
• W3170293810 cites W2921555932 @default.
• W3170293810 cites W2949694445 @default.
• W3170293810 cites W2955818047 @default.
• W3170293810 cites W2959252986 @default.
• W3170293810 cites W2990499210 @default.
• W3170293810 cites W3002254054 @default.
• W3170293810 cites W3007395396 @default.
• W3170293810 cites W3008964203 @default.
• W3170293810 cites W3010758365 @default.
• W3170293810 cites W3012794173 @default.
• W3170293810 cites W3086732142 @default.
• W3170293810 cites W3092210179 @default.
• W3170293810 doi "https://doi.org/10.1016/j.intimp.2021.107821" @default.
• W3170293810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34118644" @default.
• W3170293810 hasPublicationYear "2021" @default.
• W3170293810 type Work @default.
• W3170293810 sameAs 3170293810 @default.
• W3170293810 citedByCount "5" @default.
• W3170293810 countsByYear W31702938102021 @default.
• W3170293810 countsByYear W31702938102022 @default.
• W3170293810 countsByYear W31702938102023 @default.
• W3170293810 crossrefType "journal-article" @default.
• W3170293810 hasAuthorship W3170293810A5046597133 @default.
• W3170293810 hasAuthorship W3170293810A5056168495 @default.
• W3170293810 hasConcept C104317684 @default.
• W3170293810 hasConcept C126322002 @default.
• W3170293810 hasConcept C134018914 @default.
• W3170293810 hasConcept C148738053 @default.
• W3170293810 hasConcept C153911025 @default.
• W3170293810 hasConcept C160160445 @default.
• W3170293810 hasConcept C16685009 @default.
• W3170293810 hasConcept C167734588 @default.
• W3170293810 hasConcept C170493617 @default.
• W3170293810 hasConcept C181199279 @default.
• W3170293810 hasConcept C185592680 @default.
• W3170293810 hasConcept C198826908 @default.
• W3170293810 hasConcept C203014093 @default.
• W3170293810 hasConcept C2777025900 @default.
• W3170293810 hasConcept C2780007613 @default.
• W3170293810 hasConcept C2780394083 @default.
• W3170293810 hasConcept C2780426850 @default.
• W3170293810 hasConcept C55493867 @default.
• W3170293810 hasConcept C71924100 @default.
• W3170293810 hasConcept C86803240 @default.
• W3170293810 hasConcept C88045685 @default.
• W3170293810 hasConcept C95444343 @default.
• W3170293810 hasConceptScore W3170293810C104317684 @default.
• W3170293810 hasConceptScore W3170293810C126322002 @default.
• W3170293810 hasConceptScore W3170293810C134018914 @default.
• W3170293810 hasConceptScore W3170293810C148738053 @default.
• W3170293810 hasConceptScore W3170293810C153911025 @default.
• W3170293810 hasConceptScore W3170293810C160160445 @default.
• W3170293810 hasConceptScore W3170293810C16685009 @default.
• W3170293810 hasConceptScore W3170293810C167734588 @default.
• W3170293810 hasConceptScore W3170293810C170493617 @default.
• W3170293810 hasConceptScore W3170293810C181199279 @default.
• W3170293810 hasConceptScore W3170293810C185592680 @default.
• W3170293810 hasConceptScore W3170293810C198826908 @default.
• W3170293810 hasConceptScore W3170293810C203014093 @default.
• W3170293810 hasConceptScore W3170293810C2777025900 @default.

• next