FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3170405783> ?p ?o ?g. }

• W3170405783 endingPage "1073" @default.
• W3170405783 startingPage "1065" @default.
• W3170405783 abstract "Connective tissue disorders (CTDs) are associated with esophageal dysmotility and gastroesophageal reflux disease, which may diminish survival after lung transplantation (LTx). We studied LTx outcomes in patients with a CTD stratified by esophageal motility. We identified patients who underwent bilateral LTx from 2012 to 2017. Patients with a CTD were classified by pre-LTx diagnosis: absent esophageal motility (AEM), ineffective esophageal motility (IEM), or preserved esophageal motility (PEM). The primary endpoint was 3-year survival. Sub-analysis compared survival between the AEM group and a propensity-matched (lung allocation score), non-CTD control group. Kaplan-Meier method and log-rank test were used. In total, 495 patients underwent LTx; 33 (6.7%) had a CTD. Median (IQR) age was 62 years (55.5–67.0); 24 (72.7%) were women. Survival trended lower for recipients with a CTD than without a CTD at 1-year (84.8% vs 91.8%; p = 0.2) and 3-years (66.7% vs 73.5%; p = 0.5). Within the CTD cohort, 1- and 3-year survival was significantly higher in the PEM (100%, 87.5%) and IEM (100%, 85.7%) groups than in the AEM group (50%, 20%; p < 0.001). The AEM group had significantly lower survival at 1-year (50% vs 92.5%) and 3-years (20% vs 65%) than a lung allocation score-matched cohort of patients without a CTD. LTx recipients with a CTD and AEM had significantly lower survival than those with PEM or IEM as well as significantly lower survival than that of a propensity-matched cohort of patients without a CTD. Patients with a CTD and AEM should be considered for LTx with extreme caution and counseled appropriately. Connective tissue disorders (CTDs) are associated with esophageal dysmotility and gastroesophageal reflux disease, which may diminish survival after lung transplantation (LTx). We studied LTx outcomes in patients with a CTD stratified by esophageal motility. We identified patients who underwent bilateral LTx from 2012 to 2017. Patients with a CTD were classified by pre-LTx diagnosis: absent esophageal motility (AEM), ineffective esophageal motility (IEM), or preserved esophageal motility (PEM). The primary endpoint was 3-year survival. Sub-analysis compared survival between the AEM group and a propensity-matched (lung allocation score), non-CTD control group. Kaplan-Meier method and log-rank test were used. In total, 495 patients underwent LTx; 33 (6.7%) had a CTD. Median (IQR) age was 62 years (55.5–67.0); 24 (72.7%) were women. Survival trended lower for recipients with a CTD than without a CTD at 1-year (84.8% vs 91.8%; p = 0.2) and 3-years (66.7% vs 73.5%; p = 0.5). Within the CTD cohort, 1- and 3-year survival was significantly higher in the PEM (100%, 87.5%) and IEM (100%, 85.7%) groups than in the AEM group (50%, 20%; p < 0.001). The AEM group had significantly lower survival at 1-year (50% vs 92.5%) and 3-years (20% vs 65%) than a lung allocation score-matched cohort of patients without a CTD. LTx recipients with a CTD and AEM had significantly lower survival than those with PEM or IEM as well as significantly lower survival than that of a propensity-matched cohort of patients without a CTD. Patients with a CTD and AEM should be considered for LTx with extreme caution and counseled appropriately." @default.
• W3170405783 created "2021-06-22" @default.
• W3170405783 creator A5002289410 @default.
• W3170405783 creator A5036175788 @default.
• W3170405783 creator A5044792601 @default.
• W3170405783 creator A5044989363 @default.
• W3170405783 creator A5056718218 @default.
• W3170405783 creator A5061188627 @default.
• W3170405783 creator A5068611347 @default.
• W3170405783 creator A5076441645 @default.
• W3170405783 creator A5085893285 @default.
• W3170405783 date "2022-01-01" @default.
• W3170405783 modified "2023-10-06" @default.
• W3170405783 title "Bilateral Lung Transplant for a Connective Tissue Disorder: Esophageal Motility and 3-year Survival" @default.
• W3170405783 cites W2023804350 @default.
• W3170405783 cites W2028558343 @default.
• W3170405783 cites W2053153482 @default.
• W3170405783 cites W2055445235 @default.
• W3170405783 cites W2068453802 @default.
• W3170405783 cites W2085822011 @default.
• W3170405783 cites W2129000883 @default.
• W3170405783 cites W2154199188 @default.
• W3170405783 cites W2314586694 @default.
• W3170405783 cites W2335976060 @default.
• W3170405783 cites W2424894940 @default.
• W3170405783 cites W2771979500 @default.
• W3170405783 cites W2792980654 @default.
• W3170405783 cites W2891870254 @default.
• W3170405783 cites W2936226019 @default.
• W3170405783 cites W2965166697 @default.
• W3170405783 cites W2978898360 @default.
• W3170405783 cites W3007821459 @default.
• W3170405783 cites W4233799263 @default.
• W3170405783 doi "https://doi.org/10.1053/j.semtcvs.2021.06.004" @default.
• W3170405783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34144147" @default.
• W3170405783 hasPublicationYear "2022" @default.
• W3170405783 type Work @default.
• W3170405783 sameAs 3170405783 @default.
• W3170405783 citedByCount "4" @default.
• W3170405783 countsByYear W31704057832022 @default.
• W3170405783 countsByYear W31704057832023 @default.
• W3170405783 crossrefType "journal-article" @default.
• W3170405783 hasAuthorship W3170405783A5002289410 @default.
• W3170405783 hasAuthorship W3170405783A5036175788 @default.
• W3170405783 hasAuthorship W3170405783A5044792601 @default.
• W3170405783 hasAuthorship W3170405783A5044989363 @default.
• W3170405783 hasAuthorship W3170405783A5056718218 @default.
• W3170405783 hasAuthorship W3170405783A5061188627 @default.
• W3170405783 hasAuthorship W3170405783A5068611347 @default.
• W3170405783 hasAuthorship W3170405783A5076441645 @default.
• W3170405783 hasAuthorship W3170405783A5085893285 @default.
• W3170405783 hasConcept C111368507 @default.
• W3170405783 hasConcept C125533998 @default.
• W3170405783 hasConcept C126322002 @default.
• W3170405783 hasConcept C127313418 @default.
• W3170405783 hasConcept C141071460 @default.
• W3170405783 hasConcept C168563851 @default.
• W3170405783 hasConcept C203092338 @default.
• W3170405783 hasConcept C2776283816 @default.
• W3170405783 hasConcept C2777714996 @default.
• W3170405783 hasConcept C2777819096 @default.
• W3170405783 hasConcept C2779958274 @default.
• W3170405783 hasConcept C2780942740 @default.
• W3170405783 hasConcept C2781448352 @default.
• W3170405783 hasConcept C71924100 @default.
• W3170405783 hasConcept C72563966 @default.
• W3170405783 hasConcept C90924648 @default.
• W3170405783 hasConceptScore W3170405783C111368507 @default.
• W3170405783 hasConceptScore W3170405783C125533998 @default.
• W3170405783 hasConceptScore W3170405783C126322002 @default.
• W3170405783 hasConceptScore W3170405783C127313418 @default.
• W3170405783 hasConceptScore W3170405783C141071460 @default.
• W3170405783 hasConceptScore W3170405783C168563851 @default.
• W3170405783 hasConceptScore W3170405783C203092338 @default.
• W3170405783 hasConceptScore W3170405783C2776283816 @default.
• W3170405783 hasConceptScore W3170405783C2777714996 @default.
• W3170405783 hasConceptScore W3170405783C2777819096 @default.
• W3170405783 hasConceptScore W3170405783C2779958274 @default.
• W3170405783 hasConceptScore W3170405783C2780942740 @default.
• W3170405783 hasConceptScore W3170405783C2781448352 @default.
• W3170405783 hasConceptScore W3170405783C71924100 @default.
• W3170405783 hasConceptScore W3170405783C72563966 @default.
• W3170405783 hasConceptScore W3170405783C90924648 @default.
• W3170405783 hasIssue "3" @default.
• W3170405783 hasLocation W31704057831 @default.
• W3170405783 hasLocation W31704057832 @default.
• W3170405783 hasOpenAccess W3170405783 @default.
• W3170405783 hasPrimaryLocation W31704057831 @default.
• W3170405783 hasRelatedWork W161944863 @default.
• W3170405783 hasRelatedWork W1974890342 @default.
• W3170405783 hasRelatedWork W2052339117 @default.
• W3170405783 hasRelatedWork W2064499079 @default.
• W3170405783 hasRelatedWork W2071167854 @default.
• W3170405783 hasRelatedWork W2073030510 @default.
• W3170405783 hasRelatedWork W2104360193 @default.
• W3170405783 hasRelatedWork W2172277183 @default.
• W3170405783 hasRelatedWork W2383932286 @default.
• W3170405783 hasRelatedWork W4306253774 @default.

• next