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• W3170456212 startingPage "910" @default.
• W3170456212 abstract "The nonspecificity of doxorubicin (DOX), as well as its oral bioavailability, is a major obstacle in the clinical setting. This study was based on the change of pH value and designed for the 1st time a novel nano-matrix; multiwall carbon nanotubes (MWCNTs) coated with mesoporous silica (MS) and chitosan (CS). The latter possessed a unique nanostructure with pH-sensitivity in DOX release to be administered orally for the treatment of breast cancer. The loaded DOX and entrapment efficiency reached 64% and 99%, respectively. The results of MWCNTs@MS@CS@DOX confirmed its efficiency as pH-based drug delivery for oral breast cancer therapy." @default.
• W3170456212 created "2021-06-22" @default.
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• W3170456212 date "2021-05-30" @default.
• W3170456212 modified "2023-09-26" @default.
• W3170456212 title "Smart nanocarrier-based chitosan @silica coated carbon nanotubes composite for breast cancer treatment approach" @default.
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• W3170456212 doi "https://doi.org/10.1080/00914037.2021.1925277" @default.
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