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- W3170469219 abstract "This chapter illustrates how metabolic engineering of photosynthetic organisms offers science-based approaches enabling humanity to address some of the global challenges we are facing while facilitating the transition from fossil fuel-dependent production to a biobased society, i.e. moving from the Anthropocene Era to the Planthropocene Era. Plants are biochemists and chemists par excellence in nature, producing based on solar energy and carbon dioxide (CO2) from the atmosphere. Plant metabolic engineering involves modification of endogenous pathways to enhance, redirect, or introduce production of entirely new constituents or prevent the formation of others to meet the demands of society. This is illustrated by selected examples of metabolic engineering approaches of photosynthesis, the plant cell wall, and bioactive natural products. Metabolic engineering of plants faces numerous challenges as the plant metabolome is complex and highly dynamic, and the chemical diversity of the compounds produced is enormous. Aspects to consider are using the chloroplast as a production site or utilizing metabolic engineered microalgae as a production organism not taking up arable land. To improve the capacity of plants as production platforms, the products formed need to be stored in ways preventing autotoxicity and osmotic cellular unbalances. This may be achieved by organizing biosynthetic pathways in metabolons facilitating a high metabolic flux toward a specific product and storage of the produced compounds in biocondensates formed by liquid–liquid phase separation." @default.
- W3170469219 created "2021-06-22" @default.
- W3170469219 creator A5004416374 @default.
- W3170469219 creator A5086003526 @default.
- W3170469219 date "2021-06-04" @default.
- W3170469219 modified "2023-09-30" @default.
- W3170469219 title "Metabolic Engineering of Photosynthetic Cells – in Collaboration with Nature" @default.
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